Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP4F2 | P78329 | 3/20 | 0.47 |
| ▸ | CYP4A11 | Q02928 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP4Z1 | Q86W10 | 1/20 | 0.38 |
| ▸ | MGAM | O43451 | 1/20 | 0.38 |
| ▸ | SI | P14410 | 1/20 | 0.38 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28992199 | 0.80 | DGKA (0.41) | ALDH1A1KDM4EHSD17B10TDP1 | |
| SCHEMBL28992200 | 0.76 | NAAA (0.43) | ALDH1A1KDM4EGAACYP1A2HPGD | |
| SCHEMBL20570206 | 0.76 | NPC1 (0.39) | ALDH1A1LMNAMAPTTDP1L3MBTL1 | |
| SCHEMBL12828405 | 0.75 | CYP4F2 (0.39) | CYP4F2CYP4A11ALDH1A1LMNAMAPT | |
| SCHEMBL28992213 | 0.73 | NAAA (0.49) | ALDH1A1LMNAKDM4EMAPTGAA | |
| SCHEMBL28992178 | 0.73 | NAAA (0.49) | ALDH1A1LMNAKDM4EGAACYP1A2 | |
| SCHEMBL6515283 | 0.73 | CYP1A2 (0.41) | CYP4F2CYP4A11ALDH1A1LMNAKDM4E | |
| SCHEMBL20571647 | 0.73 | PSMB8 (0.39) | — | |
| SCHEMBL22184133 | 0.73 | NPC1 (0.43) | ALDH1A1LMNAKDM4EMAPTTDP1 | |
| SCHEMBL13838043 | 0.72 | TSHR (0.47) | ALDH1A1LMNAHSD17B10MAPTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250152728-A1 | Method And Molecules | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2025-05-15 | — | — | US | disclosed |
| US-20230321267-A1 | Method And Molecules | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2023-10-12 | — | — | US | disclosed |
| US-11759526-B2 | Method and molecules | MEDIMMUNE, LLC (US) | 2023-09-19 | — | — | US | disclosed |
| EP-4223319-A2 | METHOD AND MOLECULES | MedImmune, LLC (US) | 2023-08-09 | — | — | EP | disclosed |
| EP-3630732-B1 | METHOD AND MOLECULES | MEDIMMUNE LLC (US) | 2023-07-12 | — | — | EP | disclosed |
| US-20200206359-A1 | Method And Molecules | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2020-07-02 | — | — | US | disclosed |
| EP-3630732-A1 | METHOD AND MOLECULES | Medimmune, LLC (US) | 2020-04-08 | — | — | EP | disclosed |
| WO-2018218093-A1 | METHOD AND MOLECULES | MEDIMMUNE, LLC (US) | 2018-11-29 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250152728-A1 | Method And Molecules | PAICS, EPCAM, SQLE | CYP4F2 259/4885CYP4A11 856/4885ALDH1A1 27/4885 |
| US-20200206359-A1 | Method And Molecules | PAICS, EPCAM, SQLE | CYP4F2 259/4885CYP4A11 856/4885ALDH1A1 27/4885 |
| US-20230321267-A1 | Method And Molecules | PAICS, EPCAM, SQLE | CYP4F2 259/4885CYP4A11 856/4885ALDH1A1 27/4885 |
| US-11759526-B2 | Method and molecules | PAICS, EPCAM, SQLE | CYP4F2 259/4885CYP4A11 856/4885ALDH1A1 27/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.