Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRA | P10827 | 3/20 | 0.42 |
| ▸ | THRB | P10828 | 3/20 | 0.42 |
| ▸ | PLK1 | P53350 | 1/20 | 0.41 |
| ▸ | PLK3 | Q9H4B4 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | STING1 | Q86WV6 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | SPHK1 | Q9NYA1 | 3/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | MDH1 | P40925 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6378337 | 0.81 | MEN1 (0.44) | NPC1RAB9AALDH1A1KMT2ASMN1; SMN2 | |
| SCHEMBL6509526 | 0.75 | AR (0.42) | HPGDRAB9AALDH1A1KMT2ASMN1; SMN2 | |
| SCHEMBL7959735 | 0.72 | POLB (0.57) | THRATHRBHPGDNPC1RAB9A | |
| SCHEMBL27585167 | 0.69 | HCAR3 (0.50) | PLK1PLK3KMT2A | |
| SCHEMBL11638101 | 0.69 | ALDH1A1 (0.59) | HPGDNPC1RAB9AALDH1A1KMT2A | |
| SCHEMBL21437339 | 0.68 | PLK1 (0.56) | PLK1PLK3RAB9ASTING1ALDH1A1 | |
| SCHEMBL13570201 | 0.68 | POLB (0.66) | THRATHRBHPGDNPC1RAB9A | |
| SCHEMBL21437124 | 0.68 | PLK1 (0.58) | PLK1PLK3RAB9ASTING1ALDH1A1 | |
| SCHEMBL21437135 | 0.67 | PLK1 (0.57) | PLK1PLK3NPC1KMT2ARECQL | |
| SCHEMBL21437325 | 0.67 | PLK1 (0.57) | PLK1PLK3RAB9ASTING1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050101063-A1 | Three-terminal field-controlled molecular devices | TOUR JAMES M (US) | 2005-05-12 | — | — | US | disclosed |