Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 11/20 | 0.65 |
| ▸ | THRA | P10827 | 8/20 | 0.65 |
| ▸ | PCNA | P12004 | 7/20 | 0.65 |
| ▸ | LMNA | P02545 | 4/20 | 0.65 |
| ▸ | MEN1 | O00255 | 3/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.65 |
| ▸ | ABCB11 | O95342 | 2/20 | 0.65 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.65 |
| ▸ | PPARG | P37231 | 2/20 | 0.65 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.65 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.65 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.65 |
| ▸ | TSHR | P16473 | 1/20 | 0.65 |
| ▸ | GABRP | O00591 | 1/20 | 0.65 |
| ▸ | GABRD | O14764 | 1/20 | 0.65 |
| ▸ | F2 | P00734 | 1/20 | 0.65 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.65 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.65 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.65 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.65 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9301939 | 1.00 | THRB (0.65) | THRBTHRAPCNALMNAMEN1 | |
| SCHEMBL6515345 | 1.00 | THRB (0.65) | THRBTHRAPCNALMNAMEN1 | |
| SCHEMBL17308148 | 0.90 | THRB (0.69) | THRBTHRAPCNALMNAMEN1 | |
| SCHEMBL14509272 | 0.89 | THRB (0.68) | THRBTHRAPCNALMNAMEN1 | |
| SCHEMBL4635133 | 0.89 | THRB (0.68) | THRBTHRAPCNALMNAMEN1 | |
| SCHEMBL468740 | 0.88 | THRB (0.69) | THRBTHRAPCNALMNAMEN1 | |
| SCHEMBL468737 | 0.88 | THRB (0.69) | THRBTHRAPCNALMNAMEN1 | |
| SCHEMBL5152656 | 0.87 | THRB (0.62) | THRBTHRAPCNALMNAMEN1 | |
| SCHEMBL5152662 | 0.87 | THRB (0.62) | THRBTHRAPCNALMNAMEN1 | |
| SCHEMBL8245248 | 0.87 | THRB (0.62) | THRBTHRAPCNALMNAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5354473-A | Method for concentrating a solute by countercurrent chromatography | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE DEPARTENT OF HEALTH AND HUMAN SERVICES (US) | 1994-10-11 | — | — | US | claimed |
| US-5169984-A | One step bromoacetylation of 3,3',5-triodo-l-thyronine with bromoacetyl bromide | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 1992-12-08 | — | — | US | claimed |
| US-20050159352-A1 | Use of monocarboxylate transporter protein for thyroid hormone transport | STICHTING TOT BEVORDERING VAN DE WETENSCHAP DER ENDOCRINOLOGIE (NL) | 2005-07-21 | — | — | US | disclosed |
| US-5354473-A | Method for concentrating a solute by countercurrent chromatography | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE DEPARTENT OF HEALTH AND HUMAN SERVICES (US) | 1994-10-11 | — | — | US | disclosed |
| US-5169984-A | One step bromoacetylation of 3,3',5-triodo-l-thyronine with bromoacetyl bromide | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 1992-12-08 | — | — | US | disclosed |
| US-5169984-A | One step bromoacetylation of 3,3',5-triodo-l-thyronine with bromoacetyl bromide | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 1992-12-08 | — | — | US | disclosed |
| US-5169984-A | One step bromoacetylation of 3,3',5-triodo-l-thyronine with bromoacetyl bromide | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 1992-12-08 | — | — | US | disclosed |