Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6523648 | 0.94 | THRA (0.61) | THRATHRB | |
| SCHEMBL6520528 | 0.94 | THRA (0.59) | THRATHRB | |
| SCHEMBL6520090 | 0.92 | THRA (0.67) | THRATHRB | |
| SCHEMBL6513918 | 0.91 | THRA (0.61) | THRATHRB | |
| SCHEMBL6515753 | 0.89 | THRA (0.66) | THRATHRB | |
| SCHEMBL6520060 | 0.88 | THRB (0.67) | THRATHRB | |
| SCHEMBL6515551 | 0.87 | THRA (0.63) | THRATHRB | |
| SCHEMBL6512501 | 0.86 | THRA (0.69) | THRATHRB | |
| SCHEMBL6512776 | 0.86 | THRA (0.61) | THRATHRB | |
| SCHEMBL6512564 | 0.85 | THRA (0.68) | THRATHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050032874-A1 | Anticholesterol agents; arteriosclerosis | BAYER AKTIENGESELLSCHAFT (DE) | 2005-02-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050032874-A1 | Anticholesterol agents; arteriosclerosis | HMGCR, CYP46A1, EBP | THRA 1917/4885THRB 1835/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.