SCHEMBL651572

SCHEMBL651572

c1ccc2c(Nc3ccc(Nc4cccc5ccccc45)cc3)cccc2c1

nearest known ligand 0.87

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSD17B10 Q99714 2/20 0.87
ALDH1A1 P00352 2/20 0.87
TP53 P04637 1/20 0.87
CYP3A4 P08684 1/20 0.87
HPGD P15428 1/20 0.87
ALOX15 P16050 1/20 0.87
TSHR P16473 1/20 0.87
CDC25B P30305 1/20 0.87
ATM Q13315 1/20 0.87
RAB9A P51151 2/20 0.72
KDM4E B2RXH2 3/20 0.67
MAPT P10636 3/20 0.67
KMT2A Q03164 3/20 0.67
GAA P10253 2/20 0.67
MEN1 O00255 2/20 0.67
GLA P06280 1/20 0.67
RECQL P46063 1/20 0.67
TDP1 Q9NUW8 1/20 0.67
FADS1 O60427 1/20 0.63
EPHX2 P34913 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29619354 1.00 HSD17B10 (0.87) HSD17B10ALDH1A1TP53CYP3A4HPGD
SCHEMBL74528 0.94 HSD17B10 (0.77) HSD17B10ALDH1A1TP53CYP3A4HPGD
SCHEMBL4797443 0.94 ALDH1A1 (0.92) HSD17B10ALDH1A1TP53CYP3A4HPGD
SCHEMBL29521400 0.94 HSD17B10 (0.77) HSD17B10ALDH1A1TP53CYP3A4HPGD
SCHEMBL29609502 0.94 ALDH1A1 (0.92) HSD17B10ALDH1A1TP53CYP3A4HPGD
SCHEMBL19796 0.93 ALDH1A1 (1.00) HSD17B10ALDH1A1TP53CYP3A4HPGD
SCHEMBL29350230 0.93 ALDH1A1 (1.00) HSD17B10ALDH1A1TP53CYP3A4HPGD
Hydrochloric Acid SCHEMBL7408656 0.91 ALDH1A1 (0.96) HSD17B10ALDH1A1TP53CYP3A4HPGD
Diphenylamine SCHEMBL1072941 0.91 ALDH1A1 (0.96) HSD17B10ALDH1A1TP53CYP3A4HPGD
Ammonia Solution, Strong SCHEMBL20918916 0.91 ALDH1A1 (0.96) HSD17B10ALDH1A1TP53CYP3A4HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 464 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4608898-A1 POLYAMIDE FOAMS WITH HIGH THERMAL STABILITY BASF SE (DE) 2025-09-03 EP claimed
EP-3452547-B1 POLYAMIDE MOULDING COMPOSITION AND MOULDED ARTICLE MADE HEREFROM EMS CHEMIE AG (CH) 2025-07-16 EP claimed
WO-2024088893-A1 POLYAMIDE FOAMS WITH HIGH THERMAL STABILITY BASF SE (DE) 2024-05-02 WO claimed
US-20240010836-A1 POLYAMIDE PARTS WITH LOW FUEL PERMEATION EMS-CHEMIE AG (CH) 2024-01-11 US claimed
EP-4303259-A1 POLYAMIDE PARTS WITH LOW FUEL PERMEATION EMS-CHEMIE AG (CH) 2024-01-10 EP claimed
EP-3452547-A1 POLYAMIDE MOULDING COMPOSITION AND MOULDED ARTICLE MADE HEREFROM EMS-Patent AG (CH) 2019-03-13 EP claimed
EP-2902444-B1 Polyamide moulding compounds with flame retardant properties and very good long-term heat ageing resistance EMS PATENT AG (CH) 2018-01-17 EP claimed
WO-2017191269-A1 POLYAMIDE MOULDING COMPOSITION AND MOULDED ARTICLE MADE HEREFROM EMS-PATENT AG (CH) 2017-11-09 WO claimed
US-9200136-B2 Chlorine dioxide resistant polyethylene pipes, their preparation and use BOREALIS AG (AT) 2015-12-01 US claimed
US-20150218374-A1 POLYAMIDE MOULDING COMPOUNDS WITH FLAME-RETARDANT PROPERTIES AND VERY GOOD LONG-TERM HEAT-AGEING RESISTANCE EMS-PATENT AG (CH) 2015-08-06 US claimed
EP-2902444-A1 Polyamide moulding compounds with flame retardant properties and very good long-term heat ageing resistance EMS-PATENT AG (CH) 2015-08-05 EP claimed
US-5486298-A POLYDIMETHYLSILOXANE OR POLYETHER COPOLYMERS WITH ANTOXIDANTS DOW CORNING TORAY SILICONE COMPANY, LTD. (JP) 1996-01-23 US claimed
US-5246735-A Fraying resistance, belts, polyurethane film by impregnating fibers with hydroxy-terminated rubber and an isocyanate-terminated rubber TEIJIN LIMITED (JP) 1993-09-21 US claimed
EP-0537462-A1 Process for producing rubber-reinforcing aromatic polyamide multifilament yarn TEIJIN LIMITED (JP) 1993-04-21 EP claimed
US-4828735-A POLYETHERS, STORAGE STABILITY NIPPON OIL AND FATS CO., LTD. (JP) 1989-05-09 US claimed
EP-0108714-A1 Dibenzodioxaphosphepine and dioxaphosphocine processing stabilizers CIBA-GEIGY AG (CH) 1984-05-16 EP claimed
US-4334044-A AMINO OR IMINO GROUP REACTIVE IN THE PRESSENCE OF AN ACID-CATALYST JAPAN SYNTHETIC RUBBER CO., LTD. (JP) 1982-06-08 US claimed
US-4258116-A ORGANIC SEMICONDUCTOR CANON KABUSHIKI KAISHA (JP) 1981-03-24 US claimed
JP-2041331-A None JP disclosed
US-3941843-A Purification of N,N-di-2-naphthyl-p-phenylenediamine using a mixed solvent system THE B. F. GOODRICH COMPANY (US) 1976-03-02 US disclosed