Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A9 | P48067 | 1/20 | 0.47 |
| ▸ | SLCO1B1 | Q9Y6L6 | 2/20 | 0.43 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.38 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.38 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | ABCC3 | O15438 | 1/20 | 0.37 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.37 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.37 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | ABCB4 | P21439 | 1/20 | 0.37 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.37 |
| ▸ | ABCC2 | Q92887 | 1/20 | 0.37 |
| ▸ | SLCO1B3 | Q9NPD5 | 1/20 | 0.37 |
| ▸ | OPRM1 | P35372 | 6/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6894 | 0.95 | SLC6A9 (0.41) | SLC6A9SLCO1B1TRPV1TSHRLMNA | |
| SCHEMBL7767 | 0.90 | SLC6A9 (0.49) | SLC6A9SLCO1B1TRPV1HRH4HRH3 | |
| SCHEMBL6825 | 0.84 | LPAR1 (0.48) | SLC6A9SLCO1B1TRPV1ABCC3ABCC4 | |
| SCHEMBL6517 | 0.83 | SLC6A9 (0.40) | SLC6A9SLCO1B1TRPV1TSHRLMNA | |
| SCHEMBL2635538 | 0.83 | SLC6A9 (0.40) | SLC6A9SLCO1B1ABCC3ABCC4ABCB11 | |
| SCHEMBL5044 | 0.83 | SLCO1B1 (0.41) | SLC6A9SLCO1B1TSHRLMNANPSR1 | |
| SCHEMBL6226 | 0.82 | OPRM1 (0.44) | SLCO1B1TSHRLMNANPSR1TDP1 | |
| SCHEMBL1147 | 0.82 | OPRM1 (0.44) | SLCO1B1TSHRLMNANPSR1TDP1 | |
| SCHEMBL2636805 | 0.81 | SLCO1B1 (0.38) | SLC6A9SLCO1B1TSHRLMNANPSR1 | |
| SCHEMBL950 | 0.81 | OPRM1 (0.43) | SLCO1B1TSHRLMNANPSR1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2483252-A2 | COMPOUNDS AS LYSOPHOSPHATIDIC ACID RECEPTOR ANTAGONISTS | Amira Pharmaceuticals, Inc. (US) | 2012-08-08 | — | — | EP | disclosed |
| WO-2011041694-A2 | COMPOUNDS AS LYSOPHOSPHATIDIC ACID RECEPTOR ANTAGONISTS | AMIRA PHARMACEUTICALS, INC. (US) | 2011-04-07 | — | — | WO | disclosed |