Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.37 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.33 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.33 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.33 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | DRD1 | P21728 | 1/20 | 0.33 |
| ▸ | HRH2 | P25021 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | HTR2C | P28335 | 1/20 | 0.33 |
| ▸ | HRH1 | P35367 | 1/20 | 0.33 |
| ▸ | DRD3 | P35462 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14085901 | 0.80 | EPHX1 (0.35) | CYP1A2EPHX1CYP3A4SIGMAR1TSHR | |
| SCHEMBL21937952 | 0.79 | CYP1A2 (0.34) | CYP1A2KMT2AKDM4E | |
| SCHEMBL3097412 | 0.78 | EPHX1 (0.41) | CYP1A2EPHX1CYP3A4SIGMAR1TSHR | |
| SCHEMBL476374 | 0.77 | KMT2A (0.40) | CYP1A2EPHX1CYP3A4SIGMAR1TSHR | |
| Hydrochloric Acid SCHEMBL6624641 | 0.77 | EPHX1 (0.40) | CYP1A2EPHX1CYP3A4SIGMAR1TSHR | |
| SCHEMBL5557492 | 0.76 | CYP3A4 (0.42) | CYP1A2EPHX1CYP3A4SIGMAR1TSHR | |
| SCHEMBL1309006 | 0.76 | EPHX1 (0.41) | CYP1A2EPHX1CYP3A4SIGMAR1TSHR | |
| SCHEMBL1309780 | 0.76 | SIGMAR1 (0.39) | CYP1A2EPHX1CYP3A4SIGMAR1TSHR | |
| SCHEMBL3100009 | 0.76 | TSHR (0.41) | EPHX1TSHRLMNAPMP22HRH3 | |
| Hydrochloric Acid SCHEMBL1309098 | 0.75 | CYP3A4 (0.40) | CYP1A2EPHX1CYP3A4SIGMAR1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005047253-A1 | MELANOCORTIN RECEPTOR AGONISTS | LG LIFE SCIENCES LTD. (KR) | 2005-05-26 | — | — | WO | disclosed |