SCHEMBL6516408

SCHEMBL6516408

C=C(C)C[Si](C)(OC)c1ccccc1

nearest known ligand 0.39

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
MAPT P10636 2/20 0.39
ESR1 P03372 1/20 0.34
ESR2 Q92731 1/20 0.34
PAX8 Q06710 1/20 0.32
HPGD P15428 1/20 0.31
MEN1 O00255 1/20 0.31
GAA P10253 1/20 0.31
ALOX15 P16050 1/20 0.31
CASP1 P29466 1/20 0.31
CASP7 P55210 1/20 0.31
GFER P55789 1/20 0.31
KMT2A Q03164 1/20 0.31
GPR174 Q9BXC1 1/20 0.30
LMNA P02545 1/20 0.30
TSHR P16473 1/20 0.30
HSD17B10 Q99714 1/20 0.30
CES1 P23141 1/20 0.30
ALDH1A1 P00352 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27617409 0.79 MAPT (0.36) MAPTESR1ESR2PAX8HPGD
SCHEMBL22200091 0.76 MAPT (0.56) MAPTESR1ESR2PAX8HPGD
SCHEMBL12230436 0.76 ESR1 (0.39) MAPTESR1ESR2LMNATSHR
SCHEMBL10938874 0.76 MAPT (0.35) MAPTESR1ESR2GAA
SCHEMBL837628 0.74 ESR1 (0.35) MAPTESR1ESR2HPGDTSHR
SCHEMBL22200151 0.74 MAPT (0.40) MAPTESR1ESR2PAX8HPGD
SCHEMBL1316779 0.73 MAPT (0.41) MAPTESR1ESR2PAX8HPGD
SCHEMBL13089131 0.72 ESR1 (0.34) MAPTESR1ESR2
SCHEMBL6517713 0.72 MEN1 (0.33) MAPTESR1ESR2MEN1GAA
SCHEMBL15453577 0.71 GPR174 (0.35) MAPTESR1ESR2PAX8MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20050124747-A1 Coating composition for ink-jet recording medium and ink-jet recording medium DEUTSCHE BANK AG, NEW YORK BRANCH, AS COLLATERAL AGENT 2005-06-09 US disclosed
EP-1470928-A1 COATING COMPOSITION FOR INK-JET RECORDING MEDIUM AND INK-JET RECORDING MEDIUM Clariant International Ltd. (CH) 2004-10-27 EP disclosed
EP-1114734-A1 RESIN COMPOSITION FOR INK-JET RECORDING SHEET AND RECORDING SHEET MADE WITH THE SAME DAICEL CHEMICAL INDUSTRIES, Ltd. (JP) 2001-07-11 EP disclosed
EP-0989162-A1 THERMOPLASTIC RESIN COMPOSITION, WATER-BASED COMPOSITION, HEAT-SENSITIVE PRESSURE-SENSITIVE ADHESIVE, AND HEAT-SENSITIVE SHEET Daicel Chemical Industries, Ltd. (JP) 2000-03-29 EP disclosed