SCHEMBL837628

SCHEMBL837628

CC[Si](C)(OC)c1ccccc1

nearest known ligand 0.35

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 1/20 0.35
ESR2 Q92731 1/20 0.35
TP53 P04637 2/20 0.33
CA4 P22748 1/20 0.33
MAPT P10636 1/20 0.32
KDM4E B2RXH2 1/20 0.31
NPC1 O15118 1/20 0.31
ALDH1A1 P00352 1/20 0.31
HPGD P15428 1/20 0.31
RAB9A P51151 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31
TSHR P16473 1/20 0.31
LTA4H P09960 2/20 0.30
NQO2 P16083 1/20 0.30
POLB P06746 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15249587 0.84 ESR1 (0.37) ESR1ESR2TP53MAPTKDM4E
SCHEMBL3481489 0.83 ESR1 (0.33) ESR1ESR2TP53CA4MAPT
SCHEMBL15249588 0.83 ESR1 (0.33) ESR1ESR2TP53MAPT
SCHEMBL13089524 0.82 ESR1 (0.31) ESR1ESR2
SCHEMBL3481625 0.80 ESR1 (0.34) ESR1ESR2TP53MAPTKDM4E
SCHEMBL10938874 0.80 MAPT (0.35) ESR1ESR2CA4MAPT
SCHEMBL12230436 0.80 ESR1 (0.39) ESR1ESR2CA4MAPTALDH1A1
SCHEMBL13089131 0.80 ESR1 (0.34) ESR1ESR2CA4MAPT
SCHEMBL11680664 0.80 TP53 (0.37) ESR1ESR2TP53MAPTKDM4E
SCHEMBL3481678 0.79 LTA4H (0.36) ESR1ESR2TSHRLTA4H

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115181223-B Low-gloss matte auxiliary agent, preparation method thereof and molded body 铨盛聚碳科技股份有限公司 2023-08-29 CN claimed
CN-115181223-B Low-gloss matte auxiliary agent, preparation method thereof and molded body 铨盛聚碳科技股份有限公司 2023-08-29 CN disclosed
CN-115181223-A Low-gloss matte auxiliary agent, preparation method thereof and formed body 铨盛聚碳科技股份有限公司 2022-10-14 CN disclosed
CN-114085382-A Hydrogen-containing poly titanium boron siloxane flame retardant, and preparation method and application thereof 铨盛聚碳科技股份有限公司 2022-02-25 CN disclosed
US-9932475-B2 Temperature-resistant silicone resins THE BOEING COMPANY (US) 2018-04-03 US disclosed
US-9546237-B2 Stabilization of polymers that contain a hydrolyzable functionality BRIDGESTONE CORPORATION (JP) 2017-01-17 US disclosed
EP-2128897-B1 SILICON DIELECTRIC TREATING AGENT FOR USE AFTER ETCHING, PROCESS FOR PRODUCING SEMICONDUCTOR DEVICE, AND SEMICONDUCTOR DEVICE FUJITSU LTD (JP) 2015-05-06 EP disclosed
US-8716209-B2 Agent for post-etch treatment of silicon dielectric film, method of manufacturing semiconductor device, and semiconductor device FUJITSU LIMITED (JP) 2014-05-06 US disclosed
EP-1904415-B1 HYDROPHOBING MINERALS AND FILLER MATERIALS DOW CORNING (US) 2014-03-12 EP disclosed
US-20130331520-A1 STABILIZATION OF POLYMERS THAT CONTAIN A HYDROLYZABLE FUNCTIONALITY BRIDGESTONE CORPORATION (JP) 2013-12-12 US disclosed
US-20080286474-A1 Hydrophobing Minerals and Filler Materials DOW SILICONES CORPORATION 2008-11-20 US disclosed
EP-1904415-A2 HYDROPHOBING MINERALS AND FILLER MATERIALS Dow Corning Corporation (US) 2008-04-02 EP disclosed
WO-2007009935-A2 HYDROPHOBING MINERALS AND FILLER MATERIALS DOW CORNING CORPORATION (US) 2007-01-25 WO disclosed
EP-0292260-B1 Process for producing 1,3-bis(dicarboxyphenyl)-disiloxane derivative or dianhydride thereof HITACHI CHEMICAL CO LTD (JP) 1994-04-13 EP disclosed
US-5242917-A Curing agents for epoxy resins HITACHI CHEMICAL COMPANY, LTD. (JP) 1993-09-07 US disclosed
EP-0320211-B1 PROCESS FOR PRODUCING A TETRACARBOXYLIC ACID ANHYDRIDE HAVING DISILOXANE LINKAGE Hitachi Chemical Co., Ltd. (JP) 1993-06-16 EP disclosed
US-5166363-A Process for producing 1,3-bis(dicarboxyphenyl)-disiloxane derivative or dianhydride thereof HITACHI CHEMICAL COMPANY, LTD. (JP) 1992-11-24 US disclosed
EP-0320211-A2 Process for producing a tetracarboxylic acid anhydride having disiloxane linkage Hitachi Chemical Co., Ltd. (JP) 1989-06-14 EP disclosed
US-4831091-A USING A COORDINATION CATALYST CONTAINING A SILANETRIOL OR -DIOL AS WELL AS AN AROMATIC ESTSER; ODORLESS; STEREOSPECIFIC; PARTICLE SIZES CHISSO CORPORATION (JP) 1989-05-16 US disclosed
EP-0292260-A2 Process for producing 1,3-bis(dicarboxyphenyl)-disiloxane derivative or dianhydride thereof Hitachi Chemical Co., Ltd. (JP) 1988-11-23 EP disclosed