Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 5/20 | 0.39 |
| ▸ | ERBB2 | P04626 | 4/20 | 0.39 |
| ▸ | TTR | P02766 | 2/20 | 0.38 |
| ▸ | ALB | P02768 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | SHBG | P04278 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29757308 | 0.85 | KDM4E (0.45) | EGFRERBB2KDM4EALDH1A1MAPT | |
| SCHEMBL3641661 | 0.85 | KDM4E (0.45) | EGFRERBB2KDM4EALDH1A1MAPT | |
| SCHEMBL6517991 | 0.80 | HSPA5 (0.54) | EGFRERBB2TTRALBKDM4E | |
| SCHEMBL30487695 | 0.78 | KDM4E (0.42) | EGFRERBB2KDM4EALDH1A1MAPT | |
| SCHEMBL16595156 | 0.77 | EGFR (0.39) | EGFRERBB2KDM4EALDH1A1MAPT | |
| SCHEMBL13623361 | 0.76 | SHBG (0.53) | EGFRERBB2TTRALBKDM4E | |
| SCHEMBL1175359 | 0.76 | TTR (0.45) | TTRALBKDM4EALDH1A1MAPT | |
| SCHEMBL13623355 | 0.73 | TTR (0.42) | TTRALBKDM4EALDH1A1MAPT | |
| SCHEMBL6914086 | 0.73 | MAPT (0.46) | EGFRERBB2KDM4EALDH1A1MAPT | |
| SCHEMBL197918 | 0.73 | TTR (0.58) | EGFRERBB2TTRALBKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050009687-A1 | Titanium alkoxide catalysts for polymerization of cyclic esters and methods of polymerization | NATIONAL SCIENCE FOUNDATION | 2005-01-13 | — | — | US | disclosed |