Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 8/20 | 0.46 |
| ▸ | REN | P00797 | 4/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | F2 | P00734 | 1/20 | 0.46 |
| ▸ | LTA4H | P09960 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | PEPD | P12955 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.46 |
| ▸ | HTR2A | P28223 | 1/20 | 0.46 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.46 |
| ▸ | HRH1 | P35367 | 1/20 | 0.46 |
| ▸ | THPO | P40225 | 1/20 | 0.46 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.46 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | DPP4 | P27487 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5017112 | 1.00 | ACE (0.46) | ACERENLMNAHSD17B10KDM4E | |
| SCHEMBL1881293 | 0.84 | ACE (0.49) | ACERENLMNAHSD17B10KDM4E | |
| SCHEMBL1432569 | 0.84 | ACE (0.49) | ACERENLMNAHSD17B10KDM4E | |
| SCHEMBL1432340 | 0.84 | ACE (0.49) | ACERENLMNAHSD17B10KDM4E | |
| SCHEMBL24421007 | 0.83 | DPP4 (0.37) | ACERENLMNAHSD17B10KDM4E | |
| SCHEMBL26382615 | 0.83 | DPP4 (0.37) | ACERENLMNAHSD17B10KDM4E | |
| SCHEMBL4312891 | 0.81 | ACE (0.46) | ACERENLMNAHSD17B10KDM4E | |
| SCHEMBL2032006 | 0.81 | ACE (0.46) | ACERENLMNAHSD17B10KDM4E | |
| Hydrochloric Acid SCHEMBL10694558 | 0.79 | ACE (0.45) | ACERENLMNAHSD17B10KDM4E | |
| SCHEMBL584217 | 0.78 | ACE (0.44) | ACERENLMNAHSD17B10KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1483408-A4 | NANOSTRUCTURES CONTAINING PNA JOINING OR FUNCTIONAL ELEMENTS | NANOFRAMES INC (US) | 2005-06-22 | — | — | EP | disclosed |
| EP-1483408-A1 | NANOSTRUCTURES CONTAINING PNA JOINING OR FUNCTIONAL ELEMENTS | Nanoframes, Inc. (US) | 2004-12-08 | — | — | EP | disclosed |
| US-6716961-B2 | Chiral peptide nucleic acids with a N-aminoethyl-d-proline backbone | ISIS INNOVATION LIMITED (GB) | 2004-04-06 | — | — | US | disclosed |
| US-20030215903-A1 | Nanostructures containing PNA joining or functional elements | NANOFRAMES INC. | 2003-11-20 | — | — | US | disclosed |
| US-20030198956-A1 | Staged assembly of nanostructures | NANOFRAMES, INC. | 2003-10-23 | — | — | US | disclosed |
| WO-2003072829-A1 | NANOSTRUCTURES CONTAINING PNA JOINING OR FUNCTIONAL ELEMENTS | NANOFRAMES, INC. (US) | 2003-09-04 | — | — | WO | disclosed |
| US-20030162699-A1 | Chiral peptide nucleic acids with a n-aminoethyl-d-proline backbone | ISIS INNOVATION LIMITED (GB) | 2003-08-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030162699-A1 | Chiral peptide nucleic acids with a n-aminoethyl-d-proline backbone | POLL, HNRNPL, RNGTT | ACE 391/4885REN 918/4885LMNA 475/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.