SCHEMBL5017112

SCHEMBL5017112

CC(N)N1CCCC1C(=O)O

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ACE P12821 8/20 0.46
REN P00797 4/20 0.46
LMNA P02545 2/20 0.46
HSD17B10 Q99714 2/20 0.46
KDM4E B2RXH2 1/20 0.46
F2 P00734 1/20 0.46
LTA4H P09960 1/20 0.46
MAPT P10636 1/20 0.46
PEPD P12955 1/20 0.46
ALOX15 P16050 1/20 0.46
PTGS1 P23219 1/20 0.46
HTR2A P28223 1/20 0.46
PTGS2 P35354 1/20 0.46
HRH1 P35367 1/20 0.46
THPO P40225 1/20 0.46
PMP22 Q01453 1/20 0.46
ACE2 Q9BYF1 1/20 0.46
RAB9A P51151 1/20 0.45
CYP2C19 P33261 1/20 0.39
DPP4 P27487 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6516944 1.00 ACE (0.46) ACERENLMNAHSD17B10KDM4E
SCHEMBL1881293 0.84 ACE (0.49) ACERENLMNAHSD17B10KDM4E
SCHEMBL1432569 0.84 ACE (0.49) ACERENLMNAHSD17B10KDM4E
SCHEMBL1432340 0.84 ACE (0.49) ACERENLMNAHSD17B10KDM4E
SCHEMBL24421007 0.83 DPP4 (0.37) ACERENLMNAHSD17B10KDM4E
SCHEMBL26382615 0.83 DPP4 (0.37) ACERENLMNAHSD17B10KDM4E
SCHEMBL4312891 0.81 ACE (0.46) ACERENLMNAHSD17B10KDM4E
SCHEMBL2032006 0.81 ACE (0.46) ACERENLMNAHSD17B10KDM4E
Hydrochloric Acid SCHEMBL10694558 0.79 ACE (0.45) ACERENLMNAHSD17B10KDM4E
SCHEMBL584217 0.78 ACE (0.44) ACERENLMNAHSD17B10KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260117001-A1 FLUOROPHORE-POLYMER CONJUGATES AND USES THEREOF ERISYON INC (US) 2026-04-30 US disclosed
WO-2024076928-A1 FLUOROPHORE-POLYMER CONJUGATES AND USES THEREOF ERISYON INC. (US) 2024-04-11 WO disclosed
US-20230310625-A1 Peptide Oligonucleotide Conjugates JPMORGAN CHASE BANK, N.A. AS ADMINISTRATIVE AGENT 2023-10-05 US disclosed
EP-1513871-B1 PYRROLIDINYL PEPTIDE NUCLEIC ACIDS ISIS INNOVATION (GB) 2008-10-29 EP disclosed
US-7098321-B2 Homologous peptide nucleic acids ISIS INNOVATION LIMITED (GB) 2006-08-29 US disclosed
EP-1513871-A2 PYRROLIDINYL PEPTIDE NUCLEIC ACIDS Isis Innovation Limited (GB) 2005-03-16 EP disclosed
US-6716961-B2 Chiral peptide nucleic acids with a N-aminoethyl-d-proline backbone ISIS INNOVATION LIMITED (GB) 2004-04-06 US disclosed
US-20030228588-A1 Homologous peptide nucleic acids ISIS INNOVATION LIMITED 2003-12-11 US disclosed
US-20030162699-A1 Chiral peptide nucleic acids with a n-aminoethyl-d-proline backbone ISIS INNOVATION LIMITED (GB) 2003-08-28 US disclosed
US-20030157500-A1 Pyrrolidinyl peptide nucleic acids ISIS INNOVATION LIMITED (GB) 2003-08-21 US disclosed
WO-2003066902-A2 PYRROLIDINYL PEPTIDE NUCLEIC ACIDS ISIS INNOVATION LIMITED (GB) 2003-08-14 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030157500-A1 Pyrrolidinyl peptide nucleic acids POLRMT, POLH, PCNA ACE 3500/4885REN 3418/4885LMNA 387/4885
US-20030162699-A1 Chiral peptide nucleic acids with a n-aminoethyl-d-proline backbone POLL, HNRNPL, RNGTT ACE 391/4885REN 918/4885LMNA 475/4885
US-20030228588-A1 Homologous peptide nucleic acids HNRNPH3, PCNA, POLL ACE 3394/4885REN 3248/4885LMNA 559/4885
US-20230310625-A1 Peptide Oligonucleotide Conjugates MYOF, MUSK, MTPN ACE 812/4885REN 3918/4885LMNA 3089/4885
US-20260117001-A1 FLUOROPHORE-POLYMER CONJUGATES AND USES THEREOF QPCTL, QRFPR, CD47 ACE 3469/4885REN 3641/4885LMNA 550/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.