Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.38 |
| ▸ | GAA | P10253 | 4/20 | 0.38 |
| ▸ | POLB | P06746 | 3/20 | 0.38 |
| ▸ | HPGD | P15428 | 3/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | GSR | P00390 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | MAOA | P21397 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL105358 | 0.96 | NPC1 (0.42) | NPC1RAB9ALMNAALDH1A1GAA | |
| SCHEMBL30240935 | 0.91 | NPC1 (0.44) | NPC1RAB9ALMNAALDH1A1GAA | |
| SCHEMBL75075 | 0.91 | NPC1 (0.44) | NPC1RAB9ALMNAALDH1A1GAA | |
| SCHEMBL30485788 | 0.89 | NPC1 (0.40) | NPC1RAB9ALMNAALDH1A1GAA | |
| SCHEMBL2464472 | 0.89 | NPC1 (0.40) | NPC1RAB9ALMNAALDH1A1GAA | |
| SCHEMBL8773778 | 0.89 | NPC1 (0.40) | NPC1RAB9ALMNAALDH1A1GAA | |
| SCHEMBL2955109 | 0.89 | NPC1 (0.42) | NPC1RAB9ALMNAALDH1A1GAA | |
| 1,6-Hexanediol SCHEMBL4254054 | 0.88 | MAOB (0.41) | NPC1RAB9ALMNAALDH1A1GAA | |
| SCHEMBL9323589 | 0.88 | NPC1 (0.44) | NPC1RAB9ALMNAALDH1A1GAA | |
| SCHEMBL14596692 | 0.88 | NPC1 (0.38) | NPC1RAB9ALMNAALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0834304-B1 | Use of liposomogenic UV absorbers to protect hair | CIBA SC HOLDING AG (CH) | 2005-01-26 | — | — | EP | disclosed |
| EP-0815071-B1 | LIPOSOMOGENIC UV ABSORBERS | CIBA SC HOLDING AG (CH) | 2001-04-11 | — | — | EP | disclosed |
| US-6017556-A | PROTECTING HUMAN HAIR FROM THE DAMAGING EFFECT OF ULTRAVIOLET RADIATION BY TREATING HUMAN HAIR WITH A LIPOSOMOGENIC ULTRAVIOLET RADIATION ABSORBER | CIBA SPECIALTY CHEMICALS CORPORATION (US) | 2000-01-25 | — | — | US | disclosed |
| US-6015575-A | TRIAZINE, BENZOTRIAZOLE, BENZOPHENONE AND AMINOBENZOIC ACID DERIVATIVES AS RADIATION ABSORBERS | CIBA SPECIALTY CHEMICALS CORPORATION (US) | 2000-01-18 | — | — | US | disclosed |
| EP-0834304-A2 | Liposomogenic UV absorbers | Ciba SC Holding AG (CH) | 1998-04-08 | — | — | EP | disclosed |
| EP-0815071-A1 | LIPOSOMOGENIC UV ABSORBERS | Ciba SC Holding AG (CH) | 1998-01-07 | — | — | EP | disclosed |
| WO-1996029302-A1 | LIPOSOMOGENIC UV ABSORBERS | CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) | 1996-09-26 | — | — | WO | disclosed |