SCHEMBL105358

SCHEMBL105358

CC(C)(C)c1cc(CCCO)cc(-n2nc3ccccc3n2)c1O

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 2/20 0.42
RAB9A P51151 2/20 0.42
LMNA P02545 3/20 0.39
ALDH1A1 P00352 6/20 0.39
GAA P10253 4/20 0.39
POLB P06746 3/20 0.39
HPGD P15428 3/20 0.39
TSHR P16473 2/20 0.39
THRB P10828 1/20 0.39
KDM4E B2RXH2 4/20 0.37
MAPK1 P28482 3/20 0.37
ALOX15 P16050 2/20 0.37
HSD17B10 Q99714 1/20 0.37
GSR P00390 2/20 0.36
MAPT P10636 2/20 0.36
HTT P42858 1/20 0.36
SMN1; SMN2 Q16637 1/20 0.36
MEN1 O00255 3/20 0.36
KMT2A Q03164 3/20 0.36
GMNN O75496 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6516967 0.96 NPC1 (0.41) NPC1RAB9ALMNAALDH1A1GAA
SCHEMBL75075 0.92 NPC1 (0.44) NPC1RAB9ALMNAALDH1A1GAA
SCHEMBL30240935 0.92 NPC1 (0.44) NPC1RAB9ALMNAALDH1A1GAA
SCHEMBL2955109 0.90 NPC1 (0.42) NPC1RAB9ALMNAALDH1A1GAA
SCHEMBL19118636 0.89 NPC1 (0.40) NPC1RAB9ALMNAALDH1A1POLB
SCHEMBL9323589 0.89 NPC1 (0.44) NPC1RAB9ALMNAALDH1A1GAA
SCHEMBL14596692 0.89 NPC1 (0.38) NPC1RAB9ALMNAALDH1A1GAA
SCHEMBL14577753 0.88 LMNA (0.39) NPC1RAB9ALMNAALDH1A1GAA
SCHEMBL2464472 0.88 NPC1 (0.40) NPC1RAB9ALMNAALDH1A1GAA
SCHEMBL8773778 0.88 NPC1 (0.40) NPC1RAB9ALMNAALDH1A1GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 74 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0131468-B1 ULTRAVIOLET ABSORBING POLYMERS COMPRISING 2-HYDROXY-5-ACRYLYLOXALKYLPHENYL-2H-BENZOTRIAZOLES IOLAB CORPORATION (US) 1990-01-17 EP claimed
EP-0131468-A2 Ultraviolet absorbing polymers comprising 2-hydroxy-5-acrylyloxalkylphenyl-2H-benzotriazoles IOLAB CORPORATION (US) 1985-01-16 EP claimed
US-11884790-B2 Near-infrared shielding ultrafine particle dispersion body, near-infrared shielding intermediate film, near-infrared shielding laminated structure, and method for producing near-infrared shielding ultrafine particle dispersion body SUMITOMO METAL MINING CO., LTD. (JP) 2024-01-30 US disclosed
US-20200270401-A1 NEAR-INFRARED SHIELDING ULTRAFINE PARTICLE DISPERSION BODY, NEAR-INFRARED SHIELDING INTERMEDIATE FILM, NEAR-INFRARED SHIELDING LAMINATED STRUCTURE, AND METHOD FOR PRODUCING NEAR-INFRARED SHIELDING ULTRAFINE PARTICLE DISPERSION BODY SUMITOMO METAL MINING CO., LTD. (JP) 2020-08-27 US disclosed
CN-107207682-B Curable resin composition, cured product, and laminate 三菱瓦斯化学株式会社 2020-07-24 CN disclosed
US-10696819-B2 Ultraviolet light stabilizing polymeric filler materials INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 2020-06-30 US disclosed
EP-3647388-A1 NEAR-INFRARED-SHIELDING ULTRAFINE PARTICLE DISPERSION BODY, NEAR-INFRARED-SHIELDING INTERMEDIATE FILM, NEAR-INFRARED-SHIELDING LAMINATED STRUCTURE, AND PRODUCTION METHOD FOR NEAR-INFRARED-SHIELDING ULTRAFINE PARTICLE DISPERSION BODY Sumitomo Metal Mining Co., Ltd. (JP) 2020-05-06 EP disclosed
EP-3255072-B1 USE OF CURABLE RESIN COMPOSITION FOR HARD COAT, CURED PRODUCT, AND LAMINATE MITSUBISHI GAS CHEMICAL CO (JP) 2020-04-29 EP disclosed
US-10562996-B2 Curable resin composition, cured product, and laminate MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2020-02-18 US disclosed
CN-110662817-A Near-infrared-shielding ultrafine particle dispersion, near-infrared-shielding intermediate film, near-infrared-shielding sandwich structure, and method for producing near-infrared-shielding ultrafine particle dispersion 住友金属矿山株式会社 2020-01-07 CN disclosed
US-20190175468-A1 SUNSCREEN COMPOSITIONS CONTAINING A COMBINATION OF A LINEAR ULTRAVIOLET RADIATION-ABSORBING POLYETHER AND OTHER ULTRAVIOLET-SCREENING COMPOUNDS JOHNSON & JOHNSON CONSUMER INC. 2019-06-13 US disclosed
EP-1305298-A2 PROCESSES FOR THE PREPARATION OF BENZOTRIAZOLE UV ABSORBERS Ciba SC Holding AG (CH) 2003-05-02 EP disclosed
US-20030073779-A1 Aqueous dispersion and coated product JSR CORPORATION (JP) 2003-04-17 US disclosed
EP-1256611-A2 Aqueous dispersion and coated product JSR Corporation (JP) 2002-11-13 EP disclosed
US-20020035175-A1 Processes for the preparation of benzotriazole UV absorbers CIBA SPECIALTY CHEMICALS CORP. 2002-03-21 US disclosed
WO-2002012202-A2 PROCESSES FOR THE PREPARATION OF BENZOTRIAZOLE UV ABSORBERS CIBA SPECIALTY CHEMICALS HOLDINGS INC. (CH) 2002-02-14 WO disclosed
US-5574162-A CONTAIN REACTIVE FUNCTIONAL GROUP, I.E., HYDROXY, AMINO, ISOCYANATO, GLYCIDYLOXY, TRIHYDROXYSILYL OR TRIALKOXYSILYL, WHICH CAN BE CHEMICALLY ATTACHED TO POLYMER SUBSTRATES CIBA-GEIGY CORPORATION (US) 1996-11-12 US disclosed
EP-0389419-B1 Non-migrating 1-hydrocarbyloxy hindered amine compounds as polymer stabilizers CIBA GEIGY AG (CH) 1996-05-01 EP disclosed
US-5128309-A Recording material FUJI PHOTO FILM CO., LTD. (JP) 1992-07-07 US disclosed
EP-0389419-A1 Non-migrating 1-hydrocarbyloxy hindered amine compounds as polymer stabilizers CIBA-GEIGY AG (CH) 1990-09-26 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020035175-A1 Processes for the preparation of benzotriazole UV absorbers SULT1A1, SULT2A1, NISCH NPC1 1521/4885RAB9A 4678/4885LMNA 1811/4885
US-20190175468-A1 SUNSCREEN COMPOSITIONS CONTAINING A COMBINATION OF A LINEAR ULTRAVIOLET RADIATION-ABSORBING POLYETHER AND OTHER ULTRAVIOLET-SCREENING COMPOUNDS ERCC4, ERCC1, ERCC5 NPC1 1402/4885RAB9A 2609/4885LMNA 319/4885
US-10696819-B2 Ultraviolet light stabilizing polymeric filler materials HTT, HMBS, TTPA NPC1 3877/4885RAB9A 4589/4885LMNA 254/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.