SCHEMBL6517039

SCHEMBL6517039

O=C(O)CCNc1ccco1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
POLB P06746 5/20 0.46
KMT2A Q03164 4/20 0.46
MEN1 O00255 3/20 0.46
BLM P54132 2/20 0.46
NSD2 O96028 1/20 0.46
RXFP1 Q9HBX9 1/20 0.46
ALDH1A1 P00352 6/20 0.46
HSD17B10 Q99714 3/20 0.46
HPGD P15428 2/20 0.46
CDC25A P30304 1/20 0.44
CDC25B P30305 1/20 0.44
L3MBTL1 Q9Y468 5/20 0.43
MAPT P10636 3/20 0.43
KDM4E B2RXH2 2/20 0.43
CACNA1B Q00975 1/20 0.43
APBA1 Q02410 1/20 0.43
TDP1 Q9NUW8 1/20 0.43
AKR1C3 P42330 1/20 0.41
AKR1C2 P52895 1/20 0.41
AKR1C1 Q04828 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3685770 0.81 CYP2C19 (0.43) POLBKMT2ABLMALDH1A1HSD17B10
Hydrochloric Acid SCHEMBL11086564 0.81 CYP2C19 (0.43) POLBKMT2ABLMALDH1A1HSD17B10
SCHEMBL9869417 0.76
SCHEMBL9601731 0.73 ALDH1A1 (0.38) POLBKMT2ABLMALDH1A1HSD17B10
SCHEMBL9601734 0.73 MAPT (0.40) POLBKMT2AMEN1ALDH1A1HSD17B10
SCHEMBL15347561 0.73 NAALAD2 (0.47) POLBKMT2ABLML3MBTL1TSHR
SCHEMBL15347562 0.73 NAALAD2 (0.47) POLBKMT2ABLML3MBTL1TSHR
SCHEMBL2210122 0.72
SCHEMBL3907865 0.72 RAB9A (0.53) POLBKMT2AMEN1NSD2ALDH1A1
Oxalic Acid SCHEMBL11060067 0.72 ADORA2A (0.50) POLBALDH1A1HPGDCYP2C19SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20050009151-A1 Methods for the stereospecific and enantiomeric enrichment of beta-amino acids PHARMACIA CORPORATION 2005-01-13 US disclosed