Ammonia Solution, Strong

Ammonia Solution, Strong

SCHEMBL6517323

C=CC(=O)NC(NC(=O)C=C)C(=O)O.N

nearest known ligand 0.52

Full drug profile on Sugi Atlas →

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.52
ALDH1A1 P00352 2/20 0.39
MAPK1 P28482 1/20 0.39
TDP1 Q9NUW8 1/20 0.39
CYP2C19 P33261 1/20 0.38
LMNA P02545 1/20 0.36
TGM2 P21980 1/20 0.35
THRB P10828 1/20 0.30
RECQL P46063 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL196271 0.97 TSHR (0.54) TSHRALDH1A1MAPK1TDP1CYP2C19
SCHEMBL4108692 0.81 TSHR (0.59) TSHRALDH1A1MAPK1TDP1CYP2C19
SCHEMBL7740515 0.79 TSHR (0.38) TSHRALDH1A1MAPK1TDP1CYP2C19
SCHEMBL2437423 0.77 TSHR (0.54) TSHRALDH1A1MAPK1TDP1CYP2C19
SCHEMBL36707 0.75 TSHR (0.52) TSHRALDH1A1MAPK1TDP1CYP2C19
SCHEMBL6416447 0.75 TSHR (0.52) TSHRALDH1A1MAPK1TDP1CYP2C19
SCHEMBL1081350 0.73 TSHR (0.62) TSHRALDH1A1MAPK1TDP1CYP2C19
SCHEMBL9316415 0.73 TSHR (0.56) TSHRALDH1A1MAPK1TDP1CYP2C19
Water SCHEMBL851923 0.73 TSHR (0.50) TSHRALDH1A1MAPK1TDP1CYP2C19
SCHEMBL1488255 0.73 TSHR (0.50) TSHRALDH1A1MAPK1TDP1CYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0501846-B1 Process for coating paper and cardboard, and its use to make paper having a good smoothness HOECHST FRANCE (FR) 1995-04-26 EP claimed
US-5219619-A Coating with acrylic acid homo- or copolymer crosslinked with bisacrylamidoacetic acid SOCIETE FRANCAISE HOECHST (FR) 1993-06-15 US claimed
EP-0325065-B1 WATER-IN-OIL DISPERSIONS OF HYDROPHILIC POLYMERS BASED ON ACRYLIC ACID PARTIALLY OR FULLY NEUTRALISED WITH AMMONIA, PROCESS FOR THEIR PREPARATION AND THEIR USE IN PRINTING INK SOCIETE FRANCAISE HOECHST Société anonyme dite: (FR) 1992-07-22 EP claimed
US-4906685-A Water in oil dispersions of hydrophilic polymers based on acrylic acid partially or totally converted into the salt form with ammonia SOCIETE FRANCAISE HOECHST (FR) 1990-03-06 US claimed
US-20050129769-A1 Polymeric articles for carrying therapeutic agents ALNIS BIOSCIENCES, INC. 2005-06-16 US disclosed
EP-1531868-A2 THERAPEUTIC AGENT-CONTAINING POLYMERIC NANOARTICLES Alnis Biosciences, Inc. (US) 2005-05-25 EP disclosed
WO-2005027873-A2 THERAPEUTIC AMINOGLYCOSIDE-CONTAINING HYDROGEL NANOPARTICLES ALNIS BIOSCIENCES, INC. (US) 2005-03-31 WO disclosed
US-20040126900-A1 High affinity peptide- containing nanoparticles ALNIS BIOSCIENCES INC. 2004-07-01 US disclosed
US-20040058006-A1 High affinity nanoparticles ALNIS BIOSCIENCES, INC. 2004-03-25 US disclosed
WO-2003101425-A2 THERAPEUTIC AGENT-CONTAINING POLYMERIC NANOARTICLES ALNIS BIOSCIENCES, INC. (US) 2003-12-11 WO disclosed
EP-1276507-A2 HIGH AFFINITY PEPTIDE-CONTAINING NANOPARTICLES Alnis Biosciences, Inc. (US) 2003-01-22 EP disclosed
WO-2001078786-A2 HIGH AFFINITY PEPTIDE-CONTAINING NANOPARTICLES ALNIS BIOSCIENCES, INC. (US) 2001-10-25 WO disclosed
US-6217901-B1 POLYMERIZING POLYMER AND LIPOSOMES ALNIS, LLC 2001-04-17 US disclosed
US-5219619-A Coating with acrylic acid homo- or copolymer crosslinked with bisacrylamidoacetic acid SOCIETE FRANCAISE HOECHST (FR) 1993-06-15 US disclosed
US-4906685-A Water in oil dispersions of hydrophilic polymers based on acrylic acid partially or totally converted into the salt form with ammonia SOCIETE FRANCAISE HOECHST (FR) 1990-03-06 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050129769-A1 Polymeric articles for carrying therapeutic agents CD44, EPCAM, CLTB TSHR 1664/4885ALDH1A1 3816/4885MAPK1 4417/4885
US-20040126900-A1 High affinity peptide- containing nanoparticles LNPEP, IAPP, ACP1 TSHR 1840/4885ALDH1A1 4525/4885MAPK1 2743/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.