Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.81 |
| ▸ | CYP19A1 | P11511 | 5/20 | 0.81 |
| ▸ | PPARG | P37231 | 5/20 | 0.81 |
| ▸ | MAPT | P10636 | 5/20 | 0.81 |
| ▸ | OXER1 | Q8TDS5 | 4/20 | 0.81 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.81 |
| ▸ | RXRA | P19793 | 2/20 | 0.81 |
| ▸ | PPARA | Q07869 | 4/20 | 0.66 |
| ▸ | PTGS1 | P23219 | 4/20 | 0.65 |
| ▸ | F7 | P08709 | 3/20 | 0.65 |
| ▸ | F3 | P13726 | 3/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.65 |
| ▸ | PPARD | Q03181 | 3/20 | 0.65 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.65 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.61 |
| ▸ | MEN1 | O00255 | 2/20 | 0.61 |
| ▸ | LMNA | P02545 | 2/20 | 0.61 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.61 |
| ▸ | HPGD | P15428 | 2/20 | 0.61 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24234956 | 1.00 | ALDH1A1 (0.81) | ALDH1A1CYP19A1PPARGMAPTOXER1 | |
| SCHEMBL6517333 | 1.00 | ALDH1A1 (0.81) | ALDH1A1CYP19A1PPARGMAPTOXER1 | |
| SCHEMBL21557476 | 1.00 | ALDH1A1 (0.81) | ALDH1A1CYP19A1PPARGMAPTOXER1 | |
| SCHEMBL28185188 | 0.96 | ALDH1A1 (0.81) | ALDH1A1CYP19A1PPARGMAPTOXER1 | |
| SCHEMBL31511869 | 0.96 | ALDH1A1 (0.81) | ALDH1A1CYP19A1PPARGMAPTOXER1 | |
| SCHEMBL22128525 | 0.96 | ALDH1A1 (0.81) | ALDH1A1CYP19A1PPARGMAPTOXER1 | |
| SCHEMBL12380530 | 0.96 | ALDH1A1 (0.81) | ALDH1A1CYP19A1PPARGMAPTOXER1 | |
| SCHEMBL15529526 | 0.96 | ALDH1A1 (0.81) | ALDH1A1CYP19A1PPARGMAPTOXER1 | |
| SCHEMBL17540719 | 0.94 | ALDH1A1 (0.78) | ALDH1A1CYP19A1PPARGMAPTOXER1 | |
| SCHEMBL5886674 | 0.94 | ALDH1A1 (0.78) | ALDH1A1CYP19A1PPARGMAPTOXER1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2614848-B1 | Inhaler and capsule for an inhaler | BOEHRINGER INGELHEIM INT (DE) | 2020-07-01 | — | — | EP | disclosed |
| US-10220165-B2 | Inhalator and capsule for an inhalator | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2019-03-05 | — | — | US | disclosed |
| US-8772298-B2 | Spirocyclic heterocycles medicaments containing said compounds, use thereof and method for their production | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2014-07-08 | — | — | US | disclosed |
| US-20140182587-A1 | INHALATOR AND CAPSULE FOR AN INHALATOR | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2014-07-03 | — | — | US | disclosed |
| US-20130281461-A1 | Spirocyclic Heterocycles Medicaments Containing Said Compounds, Use Thereof And Method For Their Production | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2013-10-24 | — | — | US | disclosed |
| US-8497369-B2 | Spirocyclic heterocycles medicaments containing said compounds, use thereof and method for their production | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2013-07-30 | — | — | US | disclosed |
| EP-2614848-A1 | Inhaler and capsule for an inhaler | Boehringer Ingelheim International GmbH (DE) | 2013-07-17 | — | — | EP | disclosed |
| EP-2245026-B1 | SPIROCYCLIC HETEROCYCLES, MEDICAMENTS CONTAINING SAID COMPOUNDS, USE THEREOF AND METHOD FOR THEIR PRODUCTION | BOEHRINGER INGELHEIM INT (DE) | 2012-08-01 | — | — | EP | disclosed |
| US-20110046148-A1 | Spirocyclic Heterocycles Medicaments Containing Said Compounds, Use Thereof And Method For Their Production | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2011-02-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110046148-A1 | Spirocyclic Heterocycles Medicaments Containing Said Compounds, Use Thereof And Method For Their Production | PKD1, BPHL, CYP11B2 | ALDH1A1 1307/4885CYP19A1 760/4885PPARG 365/4885 |
| US-20130281461-A1 | Spirocyclic Heterocycles Medicaments Containing Said Compounds, Use Thereof And Method For Their Production | PKD1, BPHL, CYP11B2 | ALDH1A1 1307/4885CYP19A1 760/4885PPARG 365/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.