SCHEMBL6517360

SCHEMBL6517360

Nc1cc(C(=O)O)ccc1SSc1ccc(C(=O)O)cc1N

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 10/20 0.60
ALDH1A1 P00352 5/20 0.60
TDP1 Q9NUW8 2/20 0.60
CDC25B P30305 1/20 0.48
GAA P10253 9/20 0.47
HSD17B10 Q99714 7/20 0.47
HPGD P15428 5/20 0.47
MAPT P10636 5/20 0.47
THRB P10828 3/20 0.47
GFER P55789 3/20 0.47
HTT P42858 1/20 0.47
PLEC Q15149 1/20 0.47
L3MBTL1 Q9Y468 3/20 0.46
POLB P06746 3/20 0.46
LMNA P02545 1/20 0.46
CYP1A2 P05177 2/20 0.46
CYP2C9 P11712 2/20 0.46
CYP2C19 P33261 1/20 0.46
TSHR P16473 2/20 0.44
TP53 P04637 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7435247 0.84 KDM4E (0.57) KDM4EALDH1A1TDP1CDC25BGAA
SCHEMBL8124833 0.83 CDC25B (0.53) KDM4EALDH1A1TDP1CDC25BGAA
SCHEMBL31741292 0.83 CDC25B (0.53) KDM4EALDH1A1TDP1CDC25BGAA
SCHEMBL6516194 0.83 ALDH1A1 (0.46) KDM4EALDH1A1TDP1HSD17B10HPGD
SCHEMBL6520562 0.82 ALDH1A1 (0.44) KDM4EALDH1A1TDP1GAAHSD17B10
SCHEMBL6519272 0.82 PRKCI (0.55) KDM4EALDH1A1TDP1GAAHSD17B10
SCHEMBL79989 0.78 KDM4E (0.64) KDM4EALDH1A1TDP1CDC25BGAA
SCHEMBL29476052 0.78 KDM4E (0.64) KDM4EALDH1A1TDP1CDC25BGAA
SCHEMBL17086122 0.78 KDM4E (0.77) KDM4EALDH1A1TDP1CDC25BGAA
SCHEMBL4824967 0.78 CDC25B (0.61) KDM4EALDH1A1TDP1CDC25BGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 91 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2656882-B1 Golf ball SUMITOMO RUBBER IND (JP) 2021-06-09 EP disclosed
EP-3292893-B1 GOLF BALL SUMITOMO RUBBER IND (JP) 2021-06-09 EP disclosed
EP-3156441-B1 GOLF BALL SUMITOMO RUBBER IND (JP) 2020-11-25 EP disclosed
EP-3329971-B1 GOLF BALL SUMITOMO RUBBER IND (JP) 2020-11-18 EP disclosed
EP-2666521-B1 Golf ball SUMITOMO RUBBER IND (JP) 2020-09-02 EP disclosed
EP-2669326-B1 Golf ball SUMITOMO RUBBER IND (JP) 2019-06-12 EP disclosed
US-10286258-B2 Golf ball SUMITOMO RUBBER INDUSTRIES, LTD. (JP) 2019-05-14 US disclosed
US-10272296-B2 Golf ball SUMITOMO RUBBER INDUSTRIES, LTD. (JP) 2019-04-30 US disclosed
US-10265585-B2 Golf ball SUMITOMO RUBBER INDUSTRIES, LTD. (JP) 2019-04-23 US disclosed
EP-3329971-A1 GOLF BALL Dunlop Sports Co., Ltd. (JP) 2018-06-06 EP disclosed
US-20130005506-A1 GOLF BALL SUMITOMO RUBBER INDUSTRIES, LTD. (JP) 2013-01-03 US disclosed
US-20120172150-A1 GOLF BALL SRI SPORTS LIMITED (JP) 2012-07-05 US disclosed
US-20120172149-A1 GOLF BALL SRI SPORTS LIMITED (JP) 2012-07-05 US disclosed
CN-102526997-A Golf ball SRI SPORTS LTD 2012-07-04 CN disclosed
CN-102526995-A Golf ball SRI SPORTS LTD 2012-07-04 CN disclosed
US-20120142453-A1 GOLF BALL SRI SPORTS LIMITED (JP) 2012-06-07 US disclosed
CN-102485294-A Golf ball SRI SPORTS LTD 2012-06-06 CN disclosed
US-6919393-B2 Solid golf ball SRI SPORTS LIMITED (JP) 2005-07-19 US disclosed
US-20030144425-A1 Solid golf ball SUMITOMO RUBBER INDUSTRIES, LTD. (JP) 2003-07-31 US disclosed
US-20030144427-A1 Solid golf ball SUMITOMO RUBBER INDUSTRIES, LTD. (JP) 2003-07-31 US disclosed