SCHEMBL6517636

SCHEMBL6517636

Brc1ccc(C=C(c2ccccc2)c2ccc(Br)cc2)cc1

nearest known ligand 0.71

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 2/20 0.59
CYP19A1 P11511 2/20 0.57
CYP11B2 P19099 2/20 0.57
ESR2 Q92731 1/20 0.54
PTGS2 P35354 5/20 0.53
KDM4E B2RXH2 1/20 0.47
ALDH1A1 P00352 1/20 0.47
MAPT P10636 1/20 0.47
HPGD P15428 1/20 0.47
CYP1B1 Q16678 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6517631 1.00 ESR1 (0.59) ESR1CYP19A1CYP11B2ESR2PTGS2
SCHEMBL1652775 0.98 CYP19A1 (0.59) ESR1CYP19A1CYP11B2ESR2PTGS2
SCHEMBL987335 0.96 ESR1 (0.64) ESR1CYP19A1CYP11B2ESR2PTGS2
SCHEMBL14928213 0.96 ESR1 (0.64) ESR1CYP19A1CYP11B2ESR2PTGS2
SCHEMBL6675573 0.94 ESR1 (0.53) ESR1CYP19A1CYP11B2ESR2PTGS2
SCHEMBL6675575 0.94 ESR1 (0.53) ESR1CYP19A1CYP11B2ESR2PTGS2
SCHEMBL15607138 0.92 CYP19A1 (0.53) ESR1CYP19A1CYP11B2ESR2PTGS2
SCHEMBL21738730 0.91 ESR1 (0.62) ESR1CYP19A1CYP11B2ESR2PTGS2
SCHEMBL19660691 0.90 ALDH1A1 (0.56) ESR1CYP19A1CYP11B2ESR2PTGS2
SCHEMBL13026494 0.87 MEN1 (0.49) ESR1CYP19A1CYP11B2ESR2PTGS2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119479470-A Photo-thermal response binary information anti-counterfeiting encryption method 苏州科技大学 2025-02-18 CN disclosed
EP-1155096-B1 FLUORENE COPOLYMERS AND DEVICES MADE THEREFROM DOW GLOBAL TECHNOLOGIES INC (US) 2005-03-09 EP disclosed
US-6353083-B1 CONJUGATED COPOLYMER COMPRISING UNITS DERIVED FROM 9-SUBSTITUTED FLUORENE MONOMERS AND/OR 9,9-DISUBSTITUTED FLUORENE MONOMERS AND TWO DISTINCT RESIDUAL MONOMERIC UNITS THAT HAVE HOLE TRANSPORTING PROPERTIES THE DOW CHEMICAL COMPANY 2002-03-05 US disclosed