SCHEMBL987335

SCHEMBL987335

Brc1ccc(C(=Cc2ccccc2)c2ccccc2)cc1

nearest known ligand 0.66

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 3/20 0.64
CYP19A1 P11511 5/20 0.57
CYP11B2 P19099 2/20 0.57
CYP1B1 Q16678 1/20 0.50
PTGS2 P35354 4/20 0.49
ESR2 Q92731 2/20 0.48
CYP2D6 P10635 1/20 0.47
KDM4E B2RXH2 1/20 0.45
POLB P06746 1/20 0.45
MAPT P10636 1/20 0.45
KMT2A Q03164 1/20 0.45
NPSR1 Q6W5P4 1/20 0.45
CTDSP1 Q9GZU7 1/20 0.45
TDP1 Q9NUW8 1/20 0.45
AKR1C1 Q04828 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14928213 1.00 ESR1 (0.64) ESR1CYP19A1CYP11B2CYP1B1PTGS2
SCHEMBL6517631 0.96 ESR1 (0.59) ESR1CYP19A1CYP11B2CYP1B1PTGS2
SCHEMBL6517636 0.96 ESR1 (0.59) ESR1CYP19A1CYP11B2CYP1B1PTGS2
SCHEMBL1652775 0.94 CYP19A1 (0.59) ESR1CYP19A1CYP11B2CYP1B1PTGS2
SCHEMBL6675573 0.90 ESR1 (0.53) ESR1CYP19A1CYP11B2CYP1B1PTGS2
SCHEMBL6675575 0.90 ESR1 (0.53) ESR1CYP19A1CYP11B2CYP1B1PTGS2
SCHEMBL4612465 0.89 ESR1 (0.78) ESR1CYP19A1CYP11B2PTGS2ESR2
SCHEMBL15607138 0.88 CYP19A1 (0.53) ESR1CYP19A1CYP11B2PTGS2ESR2
SCHEMBL21738730 0.87 ESR1 (0.62) ESR1CYP19A1CYP11B2PTGS2ESR2
SCHEMBL55433 0.87 ESR1 (0.74) ESR1CYP19A1CYP11B2PTGS2ESR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114907222-B Aggregation-induced emission fluorescent probe based on TPE and application thereof 扬州大学 2024-03-26 CN claimed
CN-114907222-A TPE (thermoplastic elastomer) -based aggregation-induced emission fluorescent probe and application thereof 扬州大学 2022-08-16 CN claimed
CN-110606810-B Diamine monomer containing tetraphenylethylene-diarylamine structure, preparation method and application of diamine monomer in polyamide synthesis 吉林大学 2021-03-30 CN claimed
CN-110606810-A Diamine monomer containing tetraphenylethylene-diarylamine structure, preparation method and application of diamine monomer in polyamide synthesis 吉林大学 2019-12-24 CN claimed
CN-118085286-A Polyarylether electrochromic polymer and preparation method and application thereof 吉林大学 2024-05-28 CN disclosed
CN-118005601-A Compound with aggregation-induced emission performance and preparation method thereof 五邑大学 2024-05-10 CN disclosed
CN-114907222-B Aggregation-induced emission fluorescent probe based on TPE and application thereof 扬州大学 2024-03-26 CN disclosed
CN-116789942-A Conjugated polymer containing 9-phenoxy-10-phenylanthracene structural unit, and preparation method and application thereof 江西德璟材料科技有限公司 2023-09-22 CN disclosed
CN-114907222-A TPE (thermoplastic elastomer) -based aggregation-induced emission fluorescent probe and application thereof 扬州大学 2022-08-16 CN disclosed
CN-113004519-B Aggregation-induced luminescence electro-active polyamic acid polymer, nanofiber detection test strip and application thereof 吉林大学 2021-12-14 CN disclosed
CN-113004519-A Aggregation-induced luminescence electro-active polyamic acid polymer, nanofiber detection test strip and application thereof 吉林大学 2021-06-22 CN disclosed
CN-110606810-B Diamine monomer containing tetraphenylethylene-diarylamine structure, preparation method and application of diamine monomer in polyamide synthesis 吉林大学 2021-03-30 CN disclosed
EP-2270117-A2 Organic electroluminescence device Idemitsu Kosan Co., Ltd. (JP) 2011-01-05 EP disclosed
US-20060159959-A1 Organic electroluminescence device with organic compound layer containing lower than 500 ppm of a halogen-containing compound IDEMITSU KOSAN CO., LTD. (JP) 2006-07-20 US disclosed
US-20060147823-A1 Electrophotographic photoreceptor and charge-transporting material for electrophotographic photoreceptor TAKASAGO INTERNATIONAL CORPORATION (JP) 2006-07-06 US disclosed
US-7045950-B2 Organic electroluminescence device with organic compound layer containing lower than 500 PPM of a halogen-containing compound IDEMITSU KOSAN CO., LTD. (JP) 2006-05-16 US disclosed
WO-2004074943-A1 ELECTROPHOTOGRAPHIC PHOTORECEPTOR AND CHARGE-TRANSPORTING MATERIAL FOR ELECTROPHOTOGRAPHIC PHOTORECEPTOR TAKASAGO INTERNATIONAL CORPORATION (JP) 2004-09-02 WO disclosed
US-20040007971-A1 Organic electroluminescence device IDEMITSU KOSAN CO., LTD. (JP) 2004-01-15 US disclosed
US-6617051-B1 Organic emitting layer sandwiched between a pair of electrodes, wherein at least one organic compound layer is formed from an organic compound material having an impurity concentration of lower than 1000 ppm. IDEMITSU KOSAN CO., LTD. (JP) 2003-09-09 US disclosed
EP-1063869-A1 ORGANIC ELECTROLUMINESCENCE DEVICE IDEMITSU KOSAN COMPANY LIMITED (JP) 2000-12-27 EP disclosed