Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 3/20 | 0.46 |
| ▸ | CCKBR | P32239 | 13/20 | 0.45 |
| ▸ | OXTR | P30559 | 3/20 | 0.45 |
| ▸ | CCKAR | P32238 | 5/20 | 0.44 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6521354 | 0.94 | CCKBR (0.46) | KCNH2CCKBROXTRCCKAR | |
| SCHEMBL16498272 | 0.90 | KCNH2 (0.43) | KCNH2CCKBROXTRCCKARPTGDR2 | |
| SCHEMBL6516243 | 0.89 | CCKBR (0.49) | KCNH2CCKBROXTRCCKAR | |
| SCHEMBL1505840 | 0.86 | OXTR (0.47) | KCNH2CCKBROXTRCCKAR | |
| SCHEMBL6517624 | 0.84 | KCNH2 (0.45) | KCNH2CCKBROXTRCCKAR | |
| SCHEMBL16498120 | 0.84 | CCKBR (0.42) | KCNH2CCKBRCCKAR | |
| SCHEMBL12781055 | 0.81 | CCKBR (0.43) | KCNH2CCKBROXTRCCKAR | |
| SCHEMBL6517614 | 0.78 | TSHR (0.48) | PTGDR2 | |
| SCHEMBL16498130 | 0.78 | TSHR (0.43) | PTGDR2 | |
| SCHEMBL16498133 | 0.78 | TSHR (0.43) | PTGDR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110059043-A1 | CHEMICAL COMPOUNDS | ARROW THERAPEUTICS LIMITED (GB) | 2011-03-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110059043-A1 | CHEMICAL COMPOUNDS | CYP2E1, CNR1, CYP3A5 | KCNH2 160/4885CCKBR 180/4885OXTR 489/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.