Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.49 |
| ▸ | MAPT | P10636 | 6/20 | 0.49 |
| ▸ | GAA | P10253 | 5/20 | 0.49 |
| ▸ | CACNA2D1 | P54289 | 5/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.49 |
| ▸ | GLA | P06280 | 3/20 | 0.49 |
| ▸ | POLB | P06746 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | RECQL | P46063 | 2/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | KDM1A | O60341 | 2/20 | 0.49 |
| ▸ | MITF | O75030 | 1/20 | 0.49 |
| ▸ | RAD52 | P43351 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | ATM | Q13315 | 3/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3359450 | 1.00 | KDM4E (0.49) | KDM4EMAPTGAACACNA2D1KMT2A | |
| SCHEMBL6518865 | 1.00 | KDM4E (0.49) | KDM4EMAPTGAACACNA2D1KMT2A | |
| SCHEMBL1818692 | 0.83 | ALDH1A1 (0.47) | KDM4EMAPTKMT2AGLAMEN1 | |
| SCHEMBL1818689 | 0.83 | ALDH1A1 (0.47) | KDM4EMAPTKMT2AGLAMEN1 | |
| SCHEMBL18841463 | 0.80 | CACNA2D1 (0.59) | KDM4EMAPTCACNA2D1KMT2AMEN1 | |
| SCHEMBL14740712 | 0.79 | POLB (0.56) | KDM4EMAPTGAACACNA2D1KMT2A | |
| Trifluoroacetic Acid SCHEMBL8273518 | 0.78 | KDM4E (0.48) | KDM4EMAPTGAACACNA2D1KMT2A | |
| SCHEMBL23645086 | 0.76 | PRNP (0.55) | KDM4EMAPTGAAKMT2APOLB | |
| SCHEMBL17423272 | 0.76 | KDM4E (0.60) | KDM4EMAPTGAACACNA2D1KMT2A | |
| SCHEMBL173509 | 0.76 | TSHR (0.42) | POLBLMNAALDH1A1USP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1508345-A1 | Absorbents and devices for the reduction of small organic compounds from blood products | Cerus Corporation (US) | 2005-02-23 | — | — | EP | claimed |