SCHEMBL1818692

SCHEMBL1818692

C[C@H](Nc1c2ccccc2cc2ccccc12)C(=O)O

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.47
MEN1 O00255 3/20 0.47
KMT2A Q03164 3/20 0.47
HSD17B10 Q99714 2/20 0.47
CYP1A2 P05177 2/20 0.47
KDM4E B2RXH2 2/20 0.47
GLA P06280 2/20 0.47
HPGD P15428 2/20 0.47
CYP2C19 P33261 1/20 0.47
AKR1B1 P15121 1/20 0.44
LMNA P02545 2/20 0.41
USP2 O75604 1/20 0.41
BBOX1 O75936 2/20 0.40
EGLN1 Q9GZT9 2/20 0.40
FTO Q9C0B1 1/20 0.40
TSHR P16473 1/20 0.40
CYP2C9 P11712 1/20 0.38
MAPT P10636 1/20 0.38
MAPK1 P28482 1/20 0.38
ATM Q13315 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1818689 1.00 ALDH1A1 (0.47) ALDH1A1MEN1KMT2AHSD17B10CYP1A2
SCHEMBL7268087 0.83 L3MBTL1 (0.47) ALDH1A1MEN1KMT2AHSD17B10CYP1A2
SCHEMBL3359450 0.83 KDM4E (0.49) ALDH1A1MEN1KMT2AKDM4EGLA
SCHEMBL6518868 0.83 KDM4E (0.49) ALDH1A1MEN1KMT2AKDM4EGLA
SCHEMBL6518865 0.83 KDM4E (0.49) ALDH1A1MEN1KMT2AKDM4EGLA
SCHEMBL7596368 0.82 TSHR (0.42) ALDH1A1HSD17B10CYP1A2AKR1B1LMNA
SCHEMBL173509 0.82 TSHR (0.42) ALDH1A1HSD17B10CYP1A2AKR1B1LMNA
SCHEMBL11190798 0.82 TSHR (0.42) ALDH1A1HSD17B10CYP1A2AKR1B1LMNA
SCHEMBL3865662 0.82 PYGL (0.41) ALDH1A1MEN1KMT2AHSD17B10CYP1A2
SCHEMBL680370 0.81 AKR1B1 (0.40) ALDH1A1MEN1KMT2AHSD17B10KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 158 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250250298-A1 ONCOLYTIC PEPTIDE AND USE THEREOF RISE BIOPHARMACEUTICALS INC. (CN) 2025-08-07 US claimed
WO-2025073102-A1 ONCOLYTIC PEPTIDE AND USE THEREOF FOR INHIBITING CANCER CELL VIABILITY LT BIOPHARMA INC. (CN) 2025-04-10 WO claimed
WO-2023197129-A1 ONCOLYTIC PEPTIDE AND USE THEREOF RISE BIOPHARMACEUTICALS INC. (CN) 2023-10-19 WO claimed
CN-111909242-B Polypeptide with high affinity and specific binding of beta-catenin protein and application and synthetic method thereof 西安交通大学医学院第一附属医院 2021-12-17 CN claimed
CN-111909242-A Polypeptide with high affinity and specific binding of beta-catenin protein and application and synthetic method thereof 西安交通大学医学院第一附属医院 2020-11-10 CN claimed
US-20190241660-A1 IMMUNE-STIMULATING PEPTIDES AND CHECKPOINT INHIBITORS, AND USES THEREOF FOR TREATING CANCER INTENDET SERVICES, INC. 2019-08-08 US claimed
WO-2019113072-A1 IMMUNE-STIMULATING PEPTIDES AND CHECKPOINT INHIBITORS, AND USES THEREOF FOR TREATING CANCER INTENDET SERVICES, INC. (US) 2019-06-13 WO claimed
US-10093699-B2 Peptides with antimicrobial, anticancer and/or wound-healing promoting activities, pharmaceutical compositions containing the same, and use of the peptides with antimicrobial, anticancer and/or wound-healing promoting activities NATIONAL TSING HUA UNIVERSITY (TW) 2018-10-09 US claimed
CN-106674329-A Peptides having antimicrobial, anticancer/wound healing promoting activity and uses thereof 程家维 2017-05-17 CN claimed
US-20170129924-A1 PEPTIDES WITH ANTIMICROBIAL, ANTICANCER AND/OR WOUND-HEALING PROMOTING ACTIVITIES, PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME, AND USE OF THE PEPTIDES WITH ANTIMICROBIAL, ANTICANCER AND/OR WOUND-HEALING PROMOTING ACTIVITIES NATIONAL TSING HUA UNIVERSITY (TW) 2017-05-11 US claimed
US-6252041-B1 Depsipeptides containing non-natural amino acids NISSHIN FLOUR MILLING CO., LTD. (JP) 2001-06-26 US claimed
US-6211145-B1 PRODUCTION OF APOLYPOPROTEIN E NISSHIN FLOUR MILLING CO., LTD. (JP) 2001-04-03 US claimed
US-6034247-A REACTIG A UNSATURSATED CARBOXYLATED AMINE WITH A BASE; CYCLIZATION THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) 2000-03-07 US claimed
EP-0967222-A1 CYCLIC DEPSIPEPTIDES AND DRUGS CONTAINING THE SAME AS THE ACTIVE INGREDIENT Nisshin Flour Milling Co., Ltd. (JP) 1999-12-29 EP claimed
US-6001815-A ALZHEIMER'S DISEASE; ANTILIPEMIC AGENT NISSHIN FLOUR MILLING CO., LTD. (JP) 1999-12-14 US claimed
EP-0960885-A1 DEPSIPEPTIDES AND DRUGS CONTAINING THE SAME AS THE ACTIVE INGREDIENT Nisshin Flour Milling Co., Ltd. (JP) 1999-12-01 EP claimed
EP-0934952-A2 Peptides containing an N-substituted glycine residue Nisshin Flour Milling Co., Ltd. (JP) 1999-08-11 EP claimed
EP-0931792-A1 Depsipeptides containing non-natural amino acids Nisshin Flour Milling Co., Ltd. (JP) 1999-07-28 EP claimed
EP-0927723-A1 Bicyclic depsipeptides promoting the production of apolipoprotein E Nisshin Flour Milling Co., Ltd. (JP) 1999-07-07 EP claimed
WO-1998046577-A1 NOVEL OXAZOLIDINONES AND METHODS FOR THE SYNTHESIS AND USE OF SAME THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) 1998-10-22 WO claimed