SCHEMBL6519015

SCHEMBL6519015

N#Cc1ccc(SSc2ccc(C#N)cc2[N+](=O)[O-])c([N+](=O)[O-])c1

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
VCAM1 P19320 4/20 0.62
KAT2B Q92831 1/20 0.47
MAPT P10636 6/20 0.45
TXNRD1 Q16881 1/20 0.44
TXNRD3 Q86VQ6 1/20 0.44
TXNRD2 Q9NNW7 1/20 0.44
MAPK1 P28482 1/20 0.44
TDP1 Q9NUW8 1/20 0.44
GRIN2D O15399 1/20 0.43
GRIN3B O60391 1/20 0.43
GRIN1 Q05586 1/20 0.43
GRIN2A Q12879 1/20 0.43
GRIN2B Q13224 1/20 0.43
GRIN2C Q14957 1/20 0.43
GRIN3A Q8TCU5 1/20 0.43
MERTK Q12866 2/20 0.42
KMT2A Q03164 3/20 0.42
MEN1 O00255 2/20 0.42
LMNA P02545 1/20 0.41
PKM P14618 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2018745 0.81 PDE7A (0.62) VCAM1MAPTTXNRD1TXNRD3TXNRD2
SCHEMBL4477143 0.81 VCAM1 (0.70) VCAM1KAT2BMAPTMAPK1TDP1
SCHEMBL4255731 0.79 MAPT (0.60) VCAM1MAPTTXNRD1TXNRD3TXNRD2
SCHEMBL695747 0.79 VCAM1 (0.57) VCAM1TXNRD1TXNRD3TXNRD2TDP1
SCHEMBL8143514 0.78 VCAM1 (0.66) VCAM1KAT2BMAPTMAPK1TDP1
SCHEMBL9933797 0.78 CYP1A2 (0.57) VCAM1KAT2BMAPTMAPK1TDP1
SCHEMBL694430 0.77 VCAM1 (0.62) VCAM1TXNRD1TXNRD3TXNRD2MAPK1
SCHEMBL694367 0.77 VCAM1 (0.48) VCAM1KAT2BMAPTTXNRD1TXNRD3
SCHEMBL323126 0.76 VCAM1 (0.64) VCAM1KAT2BMAPTMAPK1TDP1
SCHEMBL7983550 0.76 VCAM1 (0.64) VCAM1KAT2BMAPTMAPK1TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 74 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3292893-B1 GOLF BALL SUMITOMO RUBBER IND (JP) 2021-06-09 EP disclosed
EP-2656882-B1 Golf ball SUMITOMO RUBBER IND (JP) 2021-06-09 EP disclosed
EP-3156441-B1 GOLF BALL SUMITOMO RUBBER IND (JP) 2020-11-25 EP disclosed
EP-3329971-B1 GOLF BALL SUMITOMO RUBBER IND (JP) 2020-11-18 EP disclosed
EP-2666521-B1 Golf ball SUMITOMO RUBBER IND (JP) 2020-09-02 EP disclosed
EP-2669326-B1 Golf ball SUMITOMO RUBBER IND (JP) 2019-06-12 EP disclosed
US-10286258-B2 Golf ball SUMITOMO RUBBER INDUSTRIES, LTD. (JP) 2019-05-14 US disclosed
US-10272296-B2 Golf ball SUMITOMO RUBBER INDUSTRIES, LTD. (JP) 2019-04-30 US disclosed
US-10265585-B2 Golf ball SUMITOMO RUBBER INDUSTRIES, LTD. (JP) 2019-04-23 US disclosed
EP-3329971-A1 GOLF BALL Dunlop Sports Co., Ltd. (JP) 2018-06-06 EP disclosed
US-20130005508-A1 GOLF BALL DUNLOP SPORTS CO. LTD. (JP) 2013-01-03 US disclosed
US-20120172149-A1 GOLF BALL SRI SPORTS LIMITED (JP) 2012-07-05 US disclosed
US-20120172150-A1 GOLF BALL SRI SPORTS LIMITED (JP) 2012-07-05 US disclosed
CN-102526997-A Golf ball SRI SPORTS LTD 2012-07-04 CN disclosed
CN-102526995-A Golf ball SRI SPORTS LTD 2012-07-04 CN disclosed
US-20120142453-A1 GOLF BALL SRI SPORTS LIMITED (JP) 2012-06-07 US disclosed
CN-102485294-A Golf ball SRI SPORTS LTD 2012-06-06 CN disclosed
US-6919393-B2 Solid golf ball SRI SPORTS LIMITED (JP) 2005-07-19 US disclosed
US-20030144425-A1 Solid golf ball SUMITOMO RUBBER INDUSTRIES, LTD. (JP) 2003-07-31 US disclosed
US-20030144427-A1 Solid golf ball SUMITOMO RUBBER INDUSTRIES, LTD. (JP) 2003-07-31 US disclosed