SCHEMBL7983550

SCHEMBL7983550

[CH2]c1ccc(C#N)cc1[N+](=O)[O-]

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
VCAM1 P19320 4/20 0.64
KAT2B Q92831 1/20 0.48
MAPT P10636 7/20 0.46
MAPK1 P28482 1/20 0.45
TDP1 Q9NUW8 1/20 0.45
GRIN2D O15399 1/20 0.44
GRIN3B O60391 1/20 0.44
GRIN1 Q05586 1/20 0.44
GRIN2A Q12879 1/20 0.44
GRIN2B Q13224 1/20 0.44
GRIN2C Q14957 1/20 0.44
GRIN3A Q8TCU5 1/20 0.44
MERTK Q12866 2/20 0.43
KMT2A Q03164 2/20 0.43
MEN1 O00255 1/20 0.43
LMNA P02545 1/20 0.42
PKM P14618 1/20 0.42
GAA P10253 1/20 0.40
HPGD P15428 1/20 0.40
CCR6 P51684 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16953147 0.85 VCAM1 (0.59) VCAM1KAT2BMAPTMAPK1TDP1
SCHEMBL4477143 0.82 VCAM1 (0.70) VCAM1KAT2BMAPTMAPK1TDP1
SCHEMBL8143514 0.79 VCAM1 (0.66) VCAM1KAT2BMAPTMAPK1TDP1
SCHEMBL203082 0.78 VCAM1 (0.64) VCAM1KAT2BMAPTMAPK1TDP1
SCHEMBL10876367 0.78 VCAM1 (0.64) VCAM1KAT2BMAPTMAPK1TDP1
SCHEMBL6516751 0.78 VCAM1 (0.64) VCAM1KAT2BMAPTMAPK1TDP1
SCHEMBL12253372 0.78 VCAM1 (1.00) VCAM1KAT2BMAPTMAPK1TDP1
SCHEMBL4056837 0.78 VCAM1 (0.64) VCAM1KAT2BMAPTMAPK1TDP1
SCHEMBL323126 0.78 VCAM1 (0.64) VCAM1KAT2BMAPTMAPK1TDP1
SCHEMBL6463 0.78 VCAM1 (1.00) VCAM1KAT2BMAPTMAPK1TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109879817-A Preparation method of mesosulfuron-methyl 扬州大学 2019-06-14 CN claimed
CN-101805265-B Synthesis method of 2-nitro-4-substituted phenylacetic acid YIXING ZHONGYU PHARMCHEM TECHNOLOGY CO LTD 2013-02-06 CN claimed
CN-101805265-A Synthesis method of 2-nitro-4-substituted phenylacetic acid YIXING ZHONGYV MEDICINE TECHNOLOGY CO LTD 2010-08-18 CN claimed
CN-109879817-A Preparation method of mesosulfuron-methyl 扬州大学 2019-06-14 CN disclosed
CN-109879817-A Preparation method of mesosulfuron-methyl 扬州大学 2019-06-14 CN disclosed
CN-101805265-B Synthesis method of 2-nitro-4-substituted phenylacetic acid YIXING ZHONGYU PHARMCHEM TECHNOLOGY CO LTD 2013-02-06 CN disclosed
CN-101805265-A Synthesis method of 2-nitro-4-substituted phenylacetic acid YIXING ZHONGYV MEDICINE TECHNOLOGY CO LTD 2010-08-18 CN disclosed
WO-2001089447-A2 ANTIFUNGAL SUBSTITUTED PROPYL TRIAZOLE COMPOUND, ITS SALT, AND PREPARATION METHODS THEREOF SECOND MILITARY MEDICAL UNIVERSITY OF PLA. (CN) 2001-11-29 WO disclosed