Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR3A | P46098 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6511338 | 0.73 | HTR3A (0.37) | HTR3AKDM4ETSHRPDE10A | |
| SCHEMBL6515667 | 0.62 | HTR3A (0.36) | HTR3APDE10A | |
| SCHEMBL6519028 | 0.61 | HTR3A (0.34) | HTR3APDE10A | |
| SCHEMBL6514327 | 0.61 | HTR3A (0.35) | HTR3APDE10A | |
| SCHEMBL9753219 | 0.57 | TLR8 (0.43) | PDE10A | |
| SCHEMBL353025 | 0.56 | CYP1A2 (0.59) | KDM4ETSHRPDE10A | |
| SCHEMBL11923730 | 0.56 | PDE10A (0.53) | HTR3AKDM4ETSHRPDE10A | |
| SCHEMBL5144279 | 0.55 | DAO (0.41) | HTR3AKDM4ETSHR | |
| SCHEMBL26619920 | 0.55 | TLR8 (0.44) | HTR3AKDM4EPDE10A | |
| SCHEMBL1104838 | 0.55 | TLR7 (0.53) | KDM4ETSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050239767-A1 | Intermolecular SNAr of the heterocycle-activated nitro and fluoro groups-application in the synthesis of polyazamacrocyclic ligands | NATIONAL SCIENCE FOUNDATION | 2005-10-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050239767-A1 | Intermolecular SNAr of the heterocycle-activated nitro and fluoro groups-application in the synthesis of polyazamacrocyclic ligands | TECR, PAICS, DCXR | HTR3A 2282/4885KDM4E 1602/4885TSHR 1079/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.