D-Glutamate

D-Glutamate

SCHEMBL6519183

NC(CCC(=O)O)C(=O)O.O=CC(=O)O

nearest known ligand 0.78

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GRM8 O00222 2/20 0.78
GRM6 O15303 2/20 0.78
GRM7 Q14831 2/20 0.78
GRM4 Q14833 2/20 0.78
GSR P00390 2/20 0.78
GRIN2D O15399 1/20 0.78
GRIN3B O60391 1/20 0.78
CYP1A2 P05177 1/20 0.78
GRIK1 P39086 1/20 0.78
GRM5 P41594 1/20 0.78
GRIA1 P42261 1/20 0.78
GRIA2 P42262 1/20 0.78
GRIA3 P42263 1/20 0.78
SLC1A3 P43003 1/20 0.78
SLC1A2 P43004 1/20 0.78
SLC1A1 P43005 1/20 0.78
GRIA4 P48058 1/20 0.78
GRIN1 Q05586 1/20 0.78
GRIN2A Q12879 1/20 0.78
GRIK2 Q13002 1/20 0.78

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Glutamic Acid SCHEMBL1469880 1.00 GRM8 (0.78) GRM8GRM6GRM7GRM4GSR
Glutamic Acid SCHEMBL5053703 0.89 GRM8 (0.82) GRM8GRM6GRM7GRM4GSR
D-Glutamate SCHEMBL910530 0.89 GRM8 (0.82) GRM8GRM6GRM7GRM4GSR
D-Glutamate SCHEMBL27856487 0.89 GRM8 (0.82) GRM8GRM6GRM7GRM4GSR
Glutamic Acid SCHEMBL910249 0.89 GRM8 (0.82) GRM8GRM6GRM7GRM4GSR
D-Glutamate SCHEMBL1332297 0.89 GRM8 (1.00) GRM8GRM6GRM7GRM4GSR
D-Glutamate SCHEMBL410241 0.89 GRM8 (1.00) GRM8GRM6GRM7GRM4GSR
D-Glutamate SCHEMBL1330824 0.89 GRM8 (1.00) GRM8GRM6GRM7GRM4GSR
D-Glutamate SCHEMBL2201 0.89 GRM8 (1.00) GRM8GRM6GRM7GRM4GSR
D-Glutamate SCHEMBL17127348 0.89 GRM8 (1.00) GRM8GRM6GRM7GRM4GSR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2021118451-A1 NON-REWETTING O/W (OIL IN WATER) EMULSIFICATION SYSTEM FOR HYDROPHOBIC COMPOUNDS ORGANOCLICK AB (SE) 2021-06-17 WO claimed
CN-102297937-A Ammonia (ammonia ion) measurement method and ammonia (ammonia ion) diagnosis/measurement kit 2011-12-28 CN claimed
CN-102297956-A Measuring method and diagnosing/measuring reagent kit for ammonia (ammonia ions) 2011-12-28 CN claimed
CN-1688188-A Method for improving GGT activity of plant, plant with improved GGT activity and preparation method thereof AJINOMOTO KK (JP) 2005-10-26 CN claimed
US-11999982-B2 Method for the fermentative production of guanidinoacetic acid EVONIK OPERATIONS GMBH (DE) 2024-06-04 US disclosed
US-20230227795-A1 METHOD FOR THE FERMENTATIVE PRODUCTION OF GUANIDINOACETIC ACID EVONIK OPERATIONS GMBH (DE) 2023-07-20 US disclosed
US-20230052708-A1 NON-REWETTING O/W (OIL IN WATER) EMULSIFICATION SYSTEM FOR HYDROPHOBIC COMPOUNDS ORGANOCLICK AB (SE) 2023-02-16 US disclosed
WO-2021118451-A1 NON-REWETTING O/W (OIL IN WATER) EMULSIFICATION SYSTEM FOR HYDROPHOBIC COMPOUNDS ORGANOCLICK AB (SE) 2021-06-17 WO disclosed
WO-2021086247-A1 FLOUROCARBON FREE AND BIOBASED OIL AND WATER BARRIER MATERIALS COMPRISING POLYELECTROLYTE COMPLEXES ORGANOCLICK AB (SE) 2021-05-06 WO disclosed
CN-109266596-A Efficiently utilize the Escherichia coli recombinant strain and its construction method of fatty acid synthesis glycine and application 中国科学院微生物研究所 2019-01-25 CN disclosed
CN-102297937-A Ammonia (ammonia ion) measurement method and ammonia (ammonia ion) diagnosis/measurement kit 2011-12-28 CN disclosed
CN-102297956-A Measuring method and diagnosing/measuring reagent kit for ammonia (ammonia ions) 2011-12-28 CN disclosed
CN-100469884-C Method for improving GGT activity of plant and method for preparing plant with improved GGT activity AJINOMOTO KK (JP) 2009-03-18 CN disclosed
CN-101353662-A Method of elevating GGT activity of plant, plant with elevated GGT activity and method of constructing the same AJINOMOTO KK (JP) 2009-01-28 CN disclosed
CN-1289677-C Method for increasing glutamic acid content of plant AJINOMOTO KK (JP) 2006-12-13 CN disclosed
CN-1688188-A Method for improving GGT activity of plant, plant with improved GGT activity and preparation method thereof AJINOMOTO KK (JP) 2005-10-26 CN disclosed
US-20050188435-A1 Method of increasing the GGT activity in plants, plants with increased GGT activity, and a method of producing such plants AJINOMOTO CO., INC. (JP) 2005-08-25 US disclosed
CN-1525814-A Method for increasing glutamate content of plants and the plants having increased glutamate content ֮����ʽ���� 2004-09-01 CN disclosed