Glutamic Acid

Glutamic Acid

SCHEMBL910249

NC=O.N[C@@H](CCC(=O)O)C(=O)O

nearest known ligand 0.82

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GRM8 O00222 2/20 0.82
GRM6 O15303 2/20 0.82
GRM7 Q14831 2/20 0.82
GRM4 Q14833 2/20 0.82
GSR P00390 2/20 0.82
GRIN2D O15399 1/20 0.82
GRIN3B O60391 1/20 0.82
CYP1A2 P05177 1/20 0.82
GRIK1 P39086 1/20 0.82
GRM5 P41594 1/20 0.82
GRIA1 P42261 1/20 0.82
GRIA2 P42262 1/20 0.82
GRIA3 P42263 1/20 0.82
SLC1A3 P43003 1/20 0.82
SLC1A2 P43004 1/20 0.82
SLC1A1 P43005 1/20 0.82
GRIA4 P48058 1/20 0.82
GRIN1 Q05586 1/20 0.82
GRIN2A Q12879 1/20 0.82
GRIK2 Q13002 1/20 0.82

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
D-Glutamate SCHEMBL910530 1.00 GRM8 (0.82) GRM8GRM6GRM7GRM4GSR
Glutamic Acid SCHEMBL27867309 0.98 GRM8 (0.78) GRM8GRM6GRM7GRM4GSR
Glutamic Acid SCHEMBL5053703 0.91 GRM8 (0.82) GRM8GRM6GRM7GRM4GSR
D-Glutamate SCHEMBL27856487 0.91 GRM8 (0.82) GRM8GRM6GRM7GRM4GSR
D-Glutamate SCHEMBL1332297 0.91 GRM8 (1.00) GRM8GRM6GRM7GRM4GSR
Glutamic Acid SCHEMBL1554237 0.91 GRM8 (1.00) GRM8GRM6GRM7GRM4GSR
D-Glutamate SCHEMBL1330484 0.91 GRM8 (1.00) GRM8GRM6GRM7GRM4GSR
Glutamic Acid SCHEMBL248800 0.91 GRM8 (1.00) GRM8GRM6GRM7GRM4GSR
D-Glutamate SCHEMBL1330824 0.91 GRM8 (1.00) GRM8GRM6GRM7GRM4GSR
D-Glutamate SCHEMBL410241 0.91 GRM8 (1.00) GRM8GRM6GRM7GRM4GSR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 67 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-120188854-A Nutritional feed based on urea and application of nutritional feed in ruminants 云南牛牛牧业股份有限公司 2025-06-24 CN claimed
CN-117512596-A Tin-copper-titanium etching solution 湖北兴福电子材料股份有限公司 2024-02-06 CN claimed
WO-2023167563-A1 COMPOSITION CONTAINING N-CARBAMYL-L-GLUTAMIC ACID FOR TREATMENT OF INFLAMMATORY DISEASES 한국생명공학연구원 2023-09-07 WO claimed
CN-108165522-B Embryonic-period supplement for improving quality of broiler chickens and promoting early growth and application thereof 中国农业科学院饲料研究所 2020-12-01 CN claimed
CN-101481336-A Preparation of N-carbamoyl-aminoglutaric acid and sodium salt thereof UNIV NANCHANG (CN) 2009-07-15 CN claimed
WO-2008116165-A9 METHODS AND SYSTEMS OF DELIVERING MEDICATION VIA INHALATION NEXT SAFETY INC (US) 2009-06-11 WO claimed
WO-2008116165-A2 METHODS AND SYSTEMS OF DELIVERING MEDICATION VIA INHALATION NEXT SAFETY, INC. (US) 2008-09-25 WO claimed
CN-121063963-B Yield-increasing liquid fertilizer containing enzymolysis clamworm and preparation method thereof 沈阳华清源农业发展有限公司 2026-02-10 CN disclosed
CN-121063963-A Efficient yield-increasing liquid fertilizer containing enzymolysis clamworm and preparation method thereof 沈阳华清源农业发展有限公司 2025-12-05 CN disclosed
CN-120188854-A Nutritional feed based on urea and application of nutritional feed in ruminants 云南牛牛牧业股份有限公司 2025-06-24 CN disclosed
CN-119605730-A Method for improving chick shell emergence weight and promoting early growth and development and application 山东农业大学 2025-03-14 CN disclosed
US-12194031-B2 Compounds for use in regulating follicle maturation AARHUS UNIVERSITET (DK) 2025-01-14 US disclosed
EP-4129285-B1 COMPOUNDS FOR USE IN REGULATING FOLLICLE MATURATION UNIV AARHUS (DK) 2024-11-20 EP disclosed
CN-101969920-A Parakeratosis inhibitor, pore shrinking agent or agent for preventing or improving rough skin, and composition for external use on the skin containing the same SHISEIDO CO LTD 2011-02-09 CN disclosed
US-20110004019-A1 Parakeratosis Inhibitor, Pore-Shrinking Agent, Or Rough Skin Inhibiting/Ameliorating Agent, And External Composition For Skin Containing The Same SHISEIDO COMPANY LTD. (JP) 2011-01-06 US disclosed
EP-2255780-A1 PARAKERATOSIS INHIBITOR, PORE SHRINKING AGENT OR AGENT FOR PREVENTING OR IMPROVING ROUGH SKIN, AND COMPOSITION FOR EXTERNAL USE ON THE SKIN CONTAINING THE SAME Shiseido Company, Ltd. (JP) 2010-12-01 EP disclosed
US-7790905-B2 Pharmaceutical propylene glycol solvate compositions MCNEIL-PPC, INC. (US) 2010-09-07 US disclosed
CN-101481336-A Preparation of N-carbamoyl-aminoglutaric acid and sodium salt thereof UNIV NANCHANG (CN) 2009-07-15 CN disclosed
US-20080066741-A1 METHODS AND SYSTEMS OF DELIVERING MEDICATION VIA INHALATION HUNTER, CHARLES ERIC 2008-03-20 US disclosed
EP-0029000-A1 Mixed salts of an alkaline earth metal and of dimethylamino ethanol of N-acyl-glutamic acids and N-acyl-aspartic acids INTERCO S.A. (CH) 1981-05-20 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110004019-A1 Parakeratosis Inhibitor, Pore-Shrinking Agent, Or Rough Skin Inhibiting/Ameliorating Agent, And External Composition For Skin Containing The Same CUTA, GLRA3, ARGLU1 GRM8 513/4885GRM6 1035/4885GRM7 353/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.