SCHEMBL6519281

SCHEMBL6519281

O=S(=O)(O)c1ccc(S)c(Sc2ccccc2)c1.[Na]

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.42
SMN1; SMN2 Q16637 2/20 0.42
SNCA P37840 1/20 0.40
MMP3 P08254 1/20 0.39
MMP8 P22894 1/20 0.39
MMP13 P45452 1/20 0.39
ALDH1A1 P00352 4/20 0.39
CA2 P00918 3/20 0.39
CA4 P22748 3/20 0.39
HSD17B10 Q99714 3/20 0.39
POLB P06746 2/20 0.39
CYP2D6 P10635 1/20 0.39
SIRT1 Q96EB6 1/20 0.37
CA12 O43570 1/20 0.36
CA1 P00915 1/20 0.36
CA3 P07451 1/20 0.36
CA6 P23280 1/20 0.36
CA7 P43166 1/20 0.36
CA9 Q16790 1/20 0.36
CA13 Q8N1Q1 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6517123 1.00 TSHR (0.42) TSHRSMN1; SMN2SNCAMMP3MMP8
SCHEMBL6519273 0.98 TSHR (0.41) TSHRSMN1; SMN2SNCAMMP3MMP8
SCHEMBL6516093 0.98 TSHR (0.41) TSHRSMN1; SMN2SNCAMMP3MMP8
SCHEMBL6516009 0.85 TSHR (0.44) TSHRSMN1; SMN2SNCAMMP3MMP8
Zinc Ion SCHEMBL6516097 0.84 MMP8 (0.39) SMN1; SMN2MMP3MMP8MMP13ALDH1A1
SCHEMBL6511102 0.84 ALDH1A1 (0.42) SMN1; SMN2MMP3MMP8MMP13ALDH1A1
SCHEMBL6511357 0.84 ALDH1A1 (0.42) SMN1; SMN2MMP3MMP8MMP13ALDH1A1
SCHEMBL6519274 0.84 MMP8 (0.39) SMN1; SMN2MMP3MMP8MMP13ALDH1A1
SCHEMBL6522347 0.83 ALDH1A1 (0.41) SMN1; SMN2MMP3MMP8MMP13ALDH1A1
SCHEMBL6511096 0.83 ALDH1A1 (0.41) SMN1; SMN2MMP3MMP8MMP13ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 61 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2656882-B1 Golf ball SUMITOMO RUBBER IND (JP) 2021-06-09 EP disclosed
EP-3292893-B1 GOLF BALL SUMITOMO RUBBER IND (JP) 2021-06-09 EP disclosed
EP-3156441-B1 GOLF BALL SUMITOMO RUBBER IND (JP) 2020-11-25 EP disclosed
EP-3329971-B1 GOLF BALL SUMITOMO RUBBER IND (JP) 2020-11-18 EP disclosed
EP-2666521-B1 Golf ball SUMITOMO RUBBER IND (JP) 2020-09-02 EP disclosed
EP-2669326-B1 Golf ball SUMITOMO RUBBER IND (JP) 2019-06-12 EP disclosed
US-10286258-B2 Golf ball SUMITOMO RUBBER INDUSTRIES, LTD. (JP) 2019-05-14 US disclosed
US-10272296-B2 Golf ball SUMITOMO RUBBER INDUSTRIES, LTD. (JP) 2019-04-30 US disclosed
US-10265585-B2 Golf ball SUMITOMO RUBBER INDUSTRIES, LTD. (JP) 2019-04-23 US disclosed
EP-3329971-A1 GOLF BALL Dunlop Sports Co., Ltd. (JP) 2018-06-06 EP disclosed
US-20130005508-A1 GOLF BALL DUNLOP SPORTS CO. LTD. (JP) 2013-01-03 US disclosed
US-20130005506-A1 GOLF BALL SUMITOMO RUBBER INDUSTRIES, LTD. (JP) 2013-01-03 US disclosed
US-20130005507-A1 GOLF BALL SUMITOMO RUBBER INDUSTRIES, LTD. (JP) 2013-01-03 US disclosed
US-20130005505-A1 GOLF BALL SUMITOMO RUBBER INDUSTRIES, LTD. (JP) 2013-01-03 US disclosed
US-20120172150-A1 GOLF BALL SRI SPORTS LIMITED (JP) 2012-07-05 US disclosed
US-20120172149-A1 GOLF BALL SRI SPORTS LIMITED (JP) 2012-07-05 US disclosed
US-20120142453-A1 GOLF BALL SRI SPORTS LIMITED (JP) 2012-06-07 US disclosed
US-6919393-B2 Solid golf ball SRI SPORTS LIMITED (JP) 2005-07-19 US disclosed
US-20030144425-A1 Solid golf ball SUMITOMO RUBBER INDUSTRIES, LTD. (JP) 2003-07-31 US disclosed
US-20030144427-A1 Solid golf ball SUMITOMO RUBBER INDUSTRIES, LTD. (JP) 2003-07-31 US disclosed