SCHEMBL651948

SCHEMBL651948

CCCCCCCCCCCCCCCCCCC(C(=O)O)C(CCCCCCCCCCCCCCCCCCO)(C(=O)O)C(CCCCCCCCCCCCCCCCCC)C(=O)O

nearest known ligand 0.51

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
HSPD1 P10809 1/20 0.51
BLM P54132 1/20 0.51
HSPE1 P61604 1/20 0.51
MEN1 O00255 2/20 0.47
KMT2A Q03164 2/20 0.47
HSD17B10 Q99714 2/20 0.47
HPGD P15428 1/20 0.47
RECQL P46063 1/20 0.47
GPR84 Q9NQS5 4/20 0.43
FFAR1 O14842 1/20 0.43
MAPT P10636 1/20 0.42
LCK P06239 1/20 0.42
PPARD Q03181 1/20 0.42
ZDHHC20 Q5W0Z9 1/20 0.42
ZDHHC2 Q9UIJ5 1/20 0.42
LMNA P02545 2/20 0.41
ALDH1A1 P00352 1/20 0.41
TSHR P16473 1/20 0.41
ACE2 Q9BYF1 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23358791 0.79 HSPD1 (0.49) HSPD1BLMHSPE1MEN1KMT2A
SCHEMBL770277 0.79 HSPD1 (0.49) HSPD1BLMHSPE1MEN1KMT2A
SCHEMBL769559 0.79 HSPD1 (0.49) HSPD1BLMHSPE1MEN1KMT2A
SCHEMBL23160690 0.79 HSPD1 (0.49) HSPD1BLMHSPE1MEN1KMT2A
SCHEMBL1838833 0.79 HSPD1 (0.49) HSPD1BLMHSPE1MEN1KMT2A
SCHEMBL28976130 0.78 HSPD1 (0.54) HSPD1BLMHSPE1MEN1KMT2A
Ethylene Glycol SCHEMBL8083787 0.78 ACE2 (0.42) HSPD1BLMHSPE1GPR84FFAR1
Ammonia Solution, Strong SCHEMBL28463035 0.77 HSPD1 (0.53) HSPD1BLMHSPE1MEN1KMT2A
SCHEMBL27210077 0.77 HSPD1 (0.57) HSPD1BLMHSPE1MEN1KMT2A
SCHEMBL19858967 0.76 HSPD1 (0.56) HSPD1BLMHSPE1MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 45 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2018389-B1 HAFNIUM COMPLEXES OF CARBAZOLYL SUBSTITUTED IMIDAZOLE LIGANDS DOW GLOBAL TECHNOLOGIES LLC (US) 2016-03-09 EP disclosed
EP-2018390-B1 ORTHO-METALLATED HAFNIUM COMPLEXES OF IMIDAZOLE LIGANDS DOW GLOBAL TECHNOLOGIES LLC (US) 2016-03-09 EP disclosed
EP-2021381-B1 HAFNIUM COMPLEXES OF HETEROCYCLIC ORGANIC LIGANDS DOW GLOBAL TECHNOLOGIES LLC (US) 2015-12-23 EP disclosed
US-9181368-B2 High activity, low molecular weight olefin polymerization process DOW GLOBAL TECHNOLOGIES LLC (US) 2015-11-10 US disclosed
US-20140066585-A1 HIGH ACTIVITY, LOW MOLECULAR WEIGHT OLEFIN POLYMERIZATION PROCESS DOW GLOBAL TECHNOLOGIES LLC (US) 2014-03-06 US disclosed
US-8604145-B2 High activity, low molecular weight olefin polymerization process DOW GLOBAL TECHNOLOGIES, LLC (US) 2013-12-10 US disclosed
US-8580976-B2 Process for preparing A 2-substituted benzofuran-3-yl borate ester DOW GLOBAL TECHNOLOGIES, LLC (US) 2013-11-12 US disclosed
US-20130102795-A1 HAFNIUM COMPLEXES OF HETEROCYCLIC ORGANIC LIGANDS DOW GLOBAL TECHNOLOGIES LLC (US) 2013-04-25 US disclosed
US-20130102789-A1 HAFNIUM COMPLEXES OF HETEROCYCLIC ORGANIC LIGANDS DOW GLOBAL TECHNOLOGIES LLC (US) 2013-04-25 US disclosed
US-20130085284-A1 HAFNIUM COMPLEXES OF HETEROCYCLIC ORGANIC LIGANDS DOW GLOBAL TECHNOLOGIES LLC (US) 2013-04-04 US disclosed
WO-2007130306-A2 ORTHO-METALLATED HAFNIUM COMPLEXES OF IMIDAZOLE LIGANDS DOW GLOBAL TECHNOLOGIES INC. (US) 2007-11-15 WO disclosed
WO-2007130242-A2 HAFNIUM COMPLEXES OF HETEROCYCLIC ORGANIC LIGANDS DOW GLOBAL TECHNOLOGIES INC. (US) 2007-11-15 WO disclosed
WO-2007037944-A2 HIGH ACTIVITY, LOW MOLECULAR WEIGHT OLEFIN POLYMERIZATION PROCESS DOW GLOBAL TECHNOLOGIES INC. (US) 2007-04-05 WO disclosed
US-20060142152-A1 Morphology controlled olefin polymerization process W. R. GRACE & CO.-CONN. 2006-06-29 US disclosed
EP-1622947-A1 HIGH ACTIVITY OLEFIN POLYMERIZATION CATALYST AND PROCESS DOW GLOBAL TECHNOLOGIES INC. (US) 2006-02-08 EP disclosed
EP-1611169-A1 MORPHOLOGY CONTROLLED OLEFIN POLYMERIZATION PROCESS DOW GLOBAL TECHNOLOGIES INC. (US) 2006-01-04 EP disclosed
US-6953764-B2 High activity olefin polymerization catalyst and process DOW GLOBAL TECHNOLOGIES INC. (US) 2005-10-11 US disclosed
WO-2004099268-A1 HIGH ACTIVITY OLEFIN POLYMERIZATION CATALYST AND PROCESS DOW GLOBAL TECHNOLOGIES INC (US) 2004-11-18 WO disclosed
US-20040220050-A1 High activity olefin polymerization catalyst and process DOW GLOBAL TECHNOLOGIES LLC 2004-11-04 US disclosed
WO-2004094487-A1 MORPHOLOGY CONTROLLED OLEFIN POLYMERIZATION PROCESS DOW GLOBAL TECHNOLOGIES, INC. (US) 2004-11-04 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130102795-A1 HAFNIUM COMPLEXES OF HETEROCYCLIC ORGANIC LIGANDS HACL2, MIA3, HAO2 HSPD1 516/4885BLM 481/4885HSPE1 515/4885
US-20130085284-A1 HAFNIUM COMPLEXES OF HETEROCYCLIC ORGANIC LIGANDS HACL2, MIA3, HAO2 HSPD1 516/4885BLM 481/4885HSPE1 515/4885
US-20130102789-A1 HAFNIUM COMPLEXES OF HETEROCYCLIC ORGANIC LIGANDS HACL2, MIA3, HAO2 HSPD1 516/4885BLM 481/4885HSPE1 515/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.