Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.77 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.65 |
| ▸ | HTT | P42858 | 1/20 | 0.63 |
| ▸ | MEN1 | O00255 | 3/20 | 0.60 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | SPR | P35270 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | HTR2A | P28223 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | P4HB | P07237 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2863772 | 0.87 | TSHR (1.00) | TSHRKMT2AHTTMEN1L3MBTL1 | |
| SCHEMBL14158941 | 0.76 | KMT2A (1.00) | TSHRKMT2AHTTMEN1L3MBTL1 | |
| SCHEMBL6524004 | 0.76 | KMT2A (0.60) | TSHRKMT2AHTTMEN1L3MBTL1 | |
| SCHEMBL14621743 | 0.72 | ALDH1A1 (0.59) | TSHRKMT2AHTTMEN1L3MBTL1 | |
| SCHEMBL21496376 | 0.71 | ALDH1A1 (0.82) | TSHRKMT2AHTTMEN1L3MBTL1 | |
| SCHEMBL28442067 | 0.71 | KMT2A (0.53) | TSHRKMT2AHTTMEN1L3MBTL1 | |
| SCHEMBL6521808 | 0.71 | KMT2A (0.53) | TSHRKMT2AHTTMEN1L3MBTL1 | |
| SCHEMBL25946349 | 0.70 | ALDH1A1 (0.74) | TSHRKMT2AHTTMEN1L3MBTL1 | |
| Hydrochloric Acid SCHEMBL21494140 | 0.70 | ALDH1A1 (0.80) | TSHRKMT2AHTTMEN1L3MBTL1 | |
| SCHEMBL13953835 | 0.70 | TSHR (0.50) | TSHRKMT2AHTTMEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110065919-A1 | 5-Substituted Indol-3-Carboxylic Acid Derivatives Exhibiting Antiviral Activity a Method for the Production and Use Thereof | OOO "BINATEKH" (RU) | 2011-03-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110065919-A1 | 5-Substituted Indol-3-Carboxylic Acid Derivatives Exhibiting Antiviral Activity a Method for the Production and Use Thereof | CBR3, IFNAR1, SIGMAR1 | TSHR 56/4885KMT2A 4466/4885HTT 4136/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.