Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 4/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.38 |
| ▸ | TUBB | P07437 | 1/20 | 0.38 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.38 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.38 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.38 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.38 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.38 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.38 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.38 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.38 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.38 |
| ▸ | TUBA1C | Q9BQE3 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL34472127 | 0.88 | ALDH1A1 (0.45) | ALDH1A1TDP1L3MBTL1LMNASMN1; SMN2 | |
| SCHEMBL34473897 | 0.83 | NPC1 (0.36) | ALDH1A1TDP1L3MBTL1LMNAMAPT | |
| SCHEMBL6520014 | 0.83 | ALDH1A1 (0.46) | ALDH1A1TDP1L3MBTL1LMNASMN1; SMN2 | |
| SCHEMBL6581247 | 0.83 | ALDH1A1 (0.46) | ALDH1A1TDP1L3MBTL1LMNASMN1; SMN2 | |
| SCHEMBL6576208 | 0.81 | TDP1 (0.45) | ALDH1A1TDP1L3MBTL1LMNASMN1; SMN2 | |
| SCHEMBL626589 | 0.80 | ALDH1A1 (0.53) | ALDH1A1TDP1L3MBTL1LMNAKMT2A | |
| SCHEMBL29524625 | 0.80 | ALDH1A1 (0.53) | ALDH1A1TDP1L3MBTL1LMNAKMT2A | |
| SCHEMBL4351741 | 0.79 | ALDH1A1 (0.46) | ALDH1A1TDP1L3MBTL1LMNASMN1; SMN2 | |
| SCHEMBL29991058 | 0.79 | ALDH1A1 (0.49) | ALDH1A1TDP1L3MBTL1LMNAKMT2A | |
| SCHEMBL17048140 | 0.79 | ALDH1A1 (0.49) | ALDH1A1TDP1L3MBTL1LMNAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1038021-A4 | COMPOUNDS AND METHODS FOR THE INHIBITION OF PROTEIN-PROTEIN INTERACTIONS | WAY JEFFREY C (US) | 2005-02-16 | — | — | EP | disclosed |
| US-20030003513-A1 | Compounds and methods for the inhibition of protein-protein interactions | WAY JEFFREY C (US) | 2003-01-02 | — | — | US | disclosed |
| US-6465192-B2 | MODULATORS OF POLYPEPTIDE BINDING ACTIVITIES; FOR USE IN THE TREATMENT, PREVENTION OF INFECTIONS AND VIRAL DISEASE | Way, Jeffrey C. | 2002-10-15 | — | — | US | disclosed |
| US-20020031780-A1 | COMPOUNDS AND METHODS FOR THE INHIBITION OF PROTEIN-PROTEIN INTERACTIONS | WAY, JEFFREY C. | 2002-03-14 | — | — | US | disclosed |
| EP-1038021-A1 | COMPOUNDS AND METHODS FOR THE INHIBITION OF PROTEIN-PROTEIN INTERACTIONS | Way, Jeffrey C. (US) | 2000-09-27 | — | — | EP | disclosed |
| WO-1999031265-A1 | COMPOUNDS AND METHODS FOR THE INHIBITION OF PROTEIN-PROTEIN INTERACTIONS | WAY JEFFREY C (US) | 1999-06-24 | — | — | WO | disclosed |