SCHEMBL6520265

SCHEMBL6520265

CCCCCCCCc1cc2sc(-c3ccnc(-c4cc(-c5cc6sc(CCCCCCCC)cc6s5)ccn4)c3)cc2s1

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LNPEP Q9UIQ6 1/20 0.36
RAB9A P51151 4/20 0.34
MAPT P10636 3/20 0.34
SMN1; SMN2 Q16637 2/20 0.34
NPC1 O15118 1/20 0.34
STAT3 P40763 1/20 0.34
ATM Q13315 1/20 0.34
L3MBTL1 Q9Y468 1/20 0.31
RARB P10826 1/20 0.31
CASP3 P42574 1/20 0.31
SENP8 Q96LD8 1/20 0.31
SENP7 Q9BQF6 1/20 0.31
SENP6 Q9GZR1 1/20 0.31
CYP1A2 P05177 1/20 0.31
CYP2D6 P10635 1/20 0.31
CYP19A1 P11511 1/20 0.31
CYP2C9 P11712 1/20 0.31
CYP2C19 P33261 1/20 0.31
KDM4E B2RXH2 3/20 0.30
HPGD P15428 2/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL844528 0.82 PRKCI (0.37) RAB9AMAPTSMN1; SMN2NPC1STAT3
SCHEMBL13859420 0.82 PRKCI (0.37) RAB9AMAPTSMN1; SMN2NPC1STAT3
SCHEMBL29946176 0.82 PRKCI (0.37) RAB9AMAPTSMN1; SMN2NPC1STAT3
SCHEMBL29631485 0.81 PRKCI (0.36) RAB9AMAPTSMN1; SMN2NPC1STAT3
SCHEMBL29669260 0.81 PRKCI (0.36) RAB9AMAPTSMN1; SMN2NPC1STAT3
SCHEMBL14575073 0.80 PRKCI (0.35) RAB9AMAPTSMN1; SMN2NPC1STAT3
SCHEMBL14846491 0.80 PRKCI (0.35) RAB9AMAPTSMN1; SMN2NPC1STAT3
SCHEMBL12263242 0.80 PTGS2 (0.37) ALDH1A1
SCHEMBL26448827 0.78 PRKCI (0.34) RAB9AMAPTSMN1; SMN2NPC1STAT3
SCHEMBL10500495 0.78 KDM4E (0.44) RAB9AMAPTSMN1; SMN2RARBKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2257601-B1 HIGH MOLECULAR EXTINCTION COEFFICIENT METAL DYES ECOLE POLYTECHNIQUE FED LAUSANNE EPFL (CH) 2019-04-10 EP disclosed
US-9716240-B2 High molecular extinction coefficient metal dyes ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE (EPFL) (CH) 2017-07-25 US disclosed
US-20110062541-A1 HIGH MOLECULAR EXTINCTION COEFFICIENT METAL DYES Changchun Applied Chemistry Institute of Chinese Academy of Sciences (CN) 2011-03-17 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110062541-A1 HIGH MOLECULAR EXTINCTION COEFFICIENT METAL DYES ANXA5, TRPM5, EPCAM LNPEP 3504/4885RAB9A 2579/4885MAPT 2652/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.