Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | HPGD | P15428 | 3/20 | 0.44 |
| ▸ | TDP2 | O95551 | 1/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | DHFR | P00374 | 1/20 | 0.38 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.37 |
| ▸ | ESR1 | P03372 | 1/20 | 0.35 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.35 |
| ▸ | TXNRD1 | Q16881 | 1/20 | 0.34 |
| ▸ | TXNRD3 | Q86VQ6 | 1/20 | 0.34 |
| ▸ | TXNRD2 | Q9NNW7 | 1/20 | 0.34 |
| ▸ | TYMP | P19971 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 3/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4941573 | 0.81 | ALDH1A1 (0.40) | MAPTALDH1A1HPGDTDP2THRB | |
| SCHEMBL6350500 | 0.76 | MAPT (0.52) | MAPTALDH1A1HPGDTDP2THRB | |
| SCHEMBL8107861 | 0.73 | DHFR (0.48) | ALDH1A1HPGDKDM4EHSD17B10DHFR | |
| SCHEMBL29787010 | 0.72 | DNMT1 (0.59) | MAPTALDH1A1HPGDTHRBKDM4E | |
| SCHEMBL29410608 | 0.72 | DNMT1 (0.59) | MAPTALDH1A1HPGDTHRBKDM4E | |
| SCHEMBL196007 | 0.72 | DNMT1 (0.59) | MAPTALDH1A1HPGDTHRBKDM4E | |
| SCHEMBL6077039 | 0.71 | ALDH1A1 (0.56) | MAPTALDH1A1HPGDTHRBKDM4E | |
| SCHEMBL31307687 | 0.70 | DNMT1 (0.57) | MAPTALDH1A1HPGDTHRBKDM4E | |
| SCHEMBL29810649 | 0.70 | DNMT1 (0.57) | MAPTALDH1A1HPGDTHRBKDM4E | |
| SCHEMBL30692007 | 0.69 | DNMT1 (0.61) | MAPTALDH1A1HPGDTHRBKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1155096-B1 | FLUORENE COPOLYMERS AND DEVICES MADE THEREFROM | DOW GLOBAL TECHNOLOGIES INC (US) | 2005-03-09 | — | — | EP | disclosed |
| US-6353083-B1 | CONJUGATED COPOLYMER COMPRISING UNITS DERIVED FROM 9-SUBSTITUTED FLUORENE MONOMERS AND/OR 9,9-DISUBSTITUTED FLUORENE MONOMERS AND TWO DISTINCT RESIDUAL MONOMERIC UNITS THAT HAVE HOLE TRANSPORTING PROPERTIES | THE DOW CHEMICAL COMPANY | 2002-03-05 | — | — | US | disclosed |
| EP-1155096-A1 | FLUORENE COPOLYMERS AND DEVICES MADE THEREFROM | THE DOW CHEMICAL COMPANY (US) | 2001-11-21 | — | — | EP | disclosed |
| WO-2000046321-A1 | FLUORENE COPOLYMERS AND DEVICES MADE THEREFROM | THE DOW CHEMICAL COMPANY (US) | 2000-08-10 | — | — | WO | disclosed |