Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALKBH5 | Q6P6C2 | 3/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 9/20 | 0.54 |
| ▸ | MAPT | P10636 | 9/20 | 0.54 |
| ▸ | MEN1 | O00255 | 8/20 | 0.54 |
| ▸ | LMNA | P02545 | 6/20 | 0.54 |
| ▸ | HTT | P42858 | 6/20 | 0.54 |
| ▸ | RAB9A | P51151 | 4/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.54 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.54 |
| ▸ | CDC7 | O00311 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.51 |
| ▸ | GAA | P10253 | 5/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | NOX4 | Q9NPH5 | 1/20 | 0.46 |
| ▸ | NOX1 | Q9Y5S8 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 3/20 | 0.43 |
| ▸ | TP53 | P04637 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23398682 | 0.82 | MAPT (0.55) | ALKBH5KMT2AMAPTMEN1LMNA | |
| SCHEMBL2085581 | 0.78 | MAPT (0.69) | KMT2AMAPTMEN1LMNAHTT | |
| SCHEMBL8592651 | 0.76 | ALDH1A1 (0.69) | ALKBH5KMT2AMAPTMEN1LMNA | |
| SCHEMBL23400761 | 0.75 | MAPT (0.57) | ALKBH5KMT2AMAPTMEN1LMNA | |
| SCHEMBL1414675 | 0.75 | MAPT (0.65) | KMT2AMAPTMEN1LMNAHTT | |
| SCHEMBL5673453 | 0.71 | MAPT (0.60) | ALKBH5KMT2AMAPTMEN1LMNA | |
| SCHEMBL11429334 | 0.70 | MAPT (0.63) | KMT2AMAPTMEN1LMNAHTT | |
| SCHEMBL5976501 | 0.70 | ALKBH5 (0.51) | ALKBH5KMT2AMAPTMEN1LMNA | |
| SCHEMBL18865500 | 0.69 | ALKBH5 (0.50) | ALKBH5KMT2AMAPTMEN1LMNA | |
| SCHEMBL23400828 | 0.69 | ALKBH5 (0.57) | ALKBH5KMT2AMAPTMEN1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1155096-B1 | FLUORENE COPOLYMERS AND DEVICES MADE THEREFROM | DOW GLOBAL TECHNOLOGIES INC (US) | 2005-03-09 | — | — | EP | disclosed |
| US-6353083-B1 | CONJUGATED COPOLYMER COMPRISING UNITS DERIVED FROM 9-SUBSTITUTED FLUORENE MONOMERS AND/OR 9,9-DISUBSTITUTED FLUORENE MONOMERS AND TWO DISTINCT RESIDUAL MONOMERIC UNITS THAT HAVE HOLE TRANSPORTING PROPERTIES | THE DOW CHEMICAL COMPANY | 2002-03-05 | — | — | US | disclosed |