SCHEMBL6521749

SCHEMBL6521749

FC(F)(F)CCC1c2ccccc2-c2ccccc21

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTR2A P28223 7/20 0.48
CA1 P00915 1/20 0.38
CA2 P00918 1/20 0.38
TDO2 P48775 1/20 0.37
HRH1 P35367 5/20 0.35
GPR3 P46089 1/20 0.34
CYP2D6 P10635 2/20 0.33
KDM4E B2RXH2 2/20 0.33
CHRM2 P08172 2/20 0.33
CHRM1 P11229 2/20 0.33
SLC6A2 P23975 2/20 0.33
ADRA1A P35348 2/20 0.33
DRD3 P35462 2/20 0.33
SLC6A3 Q01959 2/20 0.33
LMNA P02545 1/20 0.33
TP53 P04637 1/20 0.33
CYP3A4 P08684 1/20 0.33
DRD2 P14416 1/20 0.33
ADRA2B P18089 1/20 0.33
ADRA2C P18825 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5353138 0.79 HTR2A (0.64) HTR2ACA1CA2TDO2HRH1
SCHEMBL7574105 0.77 HTR2A (0.61) HTR2ACA1CA2TDO2HRH1
SCHEMBL17022715 0.77 HTR2A (0.61) HTR2ACA1CA2TDO2HRH1
Hydrochloric Acid SCHEMBL6557729 0.75 HTR2A (0.58) HTR2ACA1CA2TDO2HRH1
SCHEMBL10019084 0.73 ACHE (0.36) HTR2AGPR3CHRM2CHRM1SLC6A2
SCHEMBL3073671 0.71 HTR2A (0.54) HTR2ACA1CA2TDO2HRH1
SCHEMBL1567175 0.71 HTR2A (0.54) HTR2ACA1CA2TDO2HRH1
SCHEMBL3073670 0.71 HTR2A (0.54) HTR2ACA1CA2TDO2HRH1
SCHEMBL2231461 0.71 TDO2 (0.61) HTR2ACA1CA2TDO2HRH1
SCHEMBL5355395 0.71 HTR2A (0.54) HTR2ACA1CA2TDO2HRH1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104684888-A Fluorene compound, photopolymerization initiator containing the fluorene compound, and photosensitive composition containing the photopolymerization initiator DAITO CHEMIX CORP 2015-06-03 CN disclosed
US-6908974-B2 Catalyst composition and a process for preparing linear, isotactic polymers RIEGER BERNHARD (DE) 2005-06-21 US disclosed
US-6790922-B2 OLEFIN HOMO/COPOLYMERS, FORMED BY GAS PHASE POLYMERIZATION IN THE PRESENCE OF POLYMERIZATION CATALYSTS AND ACTIVATORS, USED AS FIBERS, SHEETS AND MOLDINGS HAVING IMPACT STRENGTH Rieger, Bernhard (DE) 2004-09-14 US disclosed
US-20030176612-A1 Linear, isotactic polymers, process for preparing same, and use thereof RIEGER BERNHARD (DE) 2003-09-18 US disclosed
US-20030166803-A1 Catalyst combination and a process for preparing linear, isotactic polymers RIEGER BERNHARD (DE) 2003-09-04 US disclosed
US-6576726-B1 Titanium, zirconium, hafnium, vanadium, niobium, or tantalum metal cyclopentylindenyl complex and alumoxane activator RIEGER BERNHARD (DE) 2003-06-10 US disclosed
US-6555643-B1 Linear, isotactic polymers, process for preparing same, and use thereof RIEGER BERNHARD (DE) 2003-04-29 US disclosed
EP-1302484-A2 Linear, isotactic polymers, process for preparing same, and use thereof Rieger, Bernhard, Prof. Dr. (DE) 2003-04-16 EP disclosed
EP-1070089-B1 LINEAR, ISOTACTIC POLYMERS, PROCESS FOR PREPARING SAME, AND USE THEREOF RIEGER BERNHARD PROF DR (DE) 2003-03-19 EP disclosed
EP-1070087-B1 A CATALYST COMBINATION AND A PROCESS FOR PREPARING LINEAR, ISOTACTIC POLYMERS RIEGER BERNHARD PROF DR (DE) 2002-07-03 EP disclosed
EP-1178057-A2 A catalyst composition and a process for preparing linear, isotactic polymers Rieger, Bernhard, Prof. Dr. (DE) 2002-02-06 EP disclosed