Oxfenicine

Oxfenicine

SCHEMBL652186

NC(C(=O)O)c1ccc(O)cc1

nearest known ligand 0.55

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSD17B10 Q99714 5/20 0.55
ALDH1A1 P00352 5/20 0.55
TDP1 Q9NUW8 5/20 0.55
KMT2A Q03164 5/20 0.55
KDM4E B2RXH2 4/20 0.55
HPGD P15428 4/20 0.55
MEN1 O00255 4/20 0.55
GRM1 Q13255 3/20 0.55
CYP2C9 P11712 3/20 0.55
GRM2 Q14416 2/20 0.55
CYP2C19 P33261 2/20 0.55
GRM8 O00222 2/20 0.53
GRM4 Q14833 2/20 0.53
CYP2D6 P10635 1/20 0.53
GRM6 O15303 1/20 0.53
SLC6A2 P23975 1/20 0.53
SLC6A4 P31645 1/20 0.53
DRD3 P35462 1/20 0.53
SRC P12931 1/20 0.50
SLC7A5 Q01650 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Oxfenicine SCHEMBL124861 1.00 HSD17B10 (0.55) HSD17B10ALDH1A1TDP1KMT2AKDM4E
Oxfenicine SCHEMBL122315 1.00 HSD17B10 (0.55) HSD17B10ALDH1A1TDP1KMT2AKDM4E
Oxfenicine SCHEMBL3492041 0.98 TDP1 (0.53) HSD17B10ALDH1A1TDP1KMT2AKDM4E
Oxfenicine SCHEMBL3500341 0.98 TDP1 (0.53) HSD17B10ALDH1A1TDP1KMT2AKDM4E
Oxfenicine SCHEMBL3492039 0.98 TDP1 (0.53) HSD17B10ALDH1A1TDP1KMT2AKDM4E
Oxfenicine SCHEMBL28362139 0.96 TDP1 (0.52) HSD17B10ALDH1A1TDP1KMT2AKDM4E
Oxfenicine SCHEMBL29849367 0.92 SRC (0.58) HSD17B10ALDH1A1TDP1KMT2AKDM4E
SCHEMBL13527786 0.90 HSD17B10 (0.61) HSD17B10ALDH1A1TDP1KMT2AKDM4E
SCHEMBL11443549 0.81 ESR1 (0.42) HSD17B10ALDH1A1TDP1KMT2AKDM4E
SCHEMBL1354759 0.81 ESR1 (0.42) HSD17B10ALDH1A1TDP1KMT2AKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1370 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119198790-B Parhydroxyphenylglycine fermentation enzyme sample detection device 上海邦林生物科技有限公司 2025-04-08 CN claimed
CN-119490425-A Method for synthesizing p-hydroxyphenylglycine based on weak alkaline environment 青岛国林新材料科技有限公司 2025-02-21 CN claimed
CN-119350197-A Continuous process for preparing D-p-hydroxyphenylglycine double salt 浙江沙星科技股份有限公司 2025-01-24 CN claimed
CN-119330894-A Method for synthesizing HO-EPCP by catalyzing DMAP 山东鑫泉医药有限公司 2025-01-21 CN claimed
CN-119198790-A Parhydroxyphenylglycine fermentation enzyme sample detection device 上海邦林生物科技有限公司 2024-12-27 CN claimed
CN-119192696-A NBR diaphragm rubber compound for liquefied natural gas and preparation method thereof 江苏冠联新材料科技股份有限公司 2024-12-27 CN claimed
CN-116354838-B Method for recycling p-hydroxyphenylglycine and o-hydroxyphenylglycine 安徽普洛生物科技有限公司 2024-12-13 CN claimed
CN-118878433-A Preparation method of D (-) p-hydroxyphenylglycine methyl ester hydrochloride 浙江昂利康制药股份有限公司 2024-11-01 CN claimed
CN-115784796-B Preparation method of chelated fertilizer for improving chelating ability of trace elements in compound fertilizer 辽宁津大肥业有限公司 2024-07-05 CN claimed
CN-113636948-B DL-p-hydroxyphenylglycine asymmetric conversion resolution waste liquid treatment method 湖北省宏源药业科技股份有限公司 2024-04-09 CN claimed
US-4148920-A CARDIOVASCULAR DISORDERS, DIABETICS, OBESITY PFIZER INC. (US) 1979-04-10 US claimed
EP-0001319-A1 Process for the preparation of hydroxyphenyl hydantoin and of hydroxyphenyl glycine, and compounds thus obtained BEECHAM GROUP PLC (GB) 1979-04-04 EP claimed
US-4113959-A METHOD FOR RESOLVING AMINO AND AMMONIUM COMPOUNDS THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 1978-09-12 US claimed
US-4111933-A PROTECTION OF FUNCTIONAL GROUPS DURING REACTION AND THEIR SUBSEQUENT RESTORATION BAYER AKTIENGESELLSCHAFT (DE) 1978-09-05 US claimed
US-4110166-A CULTIVATION, CARBOXYLIC ACID FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1978-08-29 US claimed
US-4043991-A Preparation of peptides and cephalosporins SUMITOMO CHEMICAL COMPANY, LIMITED (JA) 1977-08-23 US claimed
US-4016205-A Process for the optical resolution of DL-2-(4-hydroxyphenyl)glycine FUJISAWA PHARMACEUTICAL CO., LTD. (JA) 1977-04-05 US claimed
US-4007168-A Process for preparing penicillins derivatives PALOMO COLL A L 1977-02-08 US claimed
US-4002666-A SALT FORMATION WITH PHENYLETHYLAMINE, DECOMPOSITION, HYDROLYSIS NIPPON KAYAKU KABUSHIKI KAISHA (JA) 1977-01-11 US claimed
US-3935014-A Direct-positive photographic emulsion containing, unfogged, monodispersed silver halide grains having a layered grain structure of specific silver chloride content AGFA-GEVAERT AKTIENGESELLSCHAFT (DT) 1976-01-27 US claimed