Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 6/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.52 |
| ▸ | HPGD | P15428 | 4/20 | 0.52 |
| ▸ | MEN1 | O00255 | 4/20 | 0.52 |
| ▸ | GRM1 | Q13255 | 3/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.52 |
| ▸ | GRM2 | Q14416 | 2/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.52 |
| ▸ | GRM8 | O00222 | 2/20 | 0.50 |
| ▸ | GRM4 | Q14833 | 2/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.50 |
| ▸ | GRM6 | O15303 | 1/20 | 0.50 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.50 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.50 |
| ▸ | DRD3 | P35462 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Oxfenicine SCHEMBL122315 | 0.96 | HSD17B10 (0.55) | TDP1HSD17B10ALDH1A1KMT2AKDM4E | |
| Oxfenicine SCHEMBL124861 | 0.96 | HSD17B10 (0.55) | TDP1HSD17B10ALDH1A1KMT2AKDM4E | |
| Oxfenicine SCHEMBL652186 | 0.96 | HSD17B10 (0.55) | TDP1HSD17B10ALDH1A1KMT2AKDM4E | |
| Oxfenicine SCHEMBL3492041 | 0.93 | TDP1 (0.53) | TDP1HSD17B10ALDH1A1KMT2AKDM4E | |
| Oxfenicine SCHEMBL3500341 | 0.93 | TDP1 (0.53) | TDP1HSD17B10ALDH1A1KMT2AKDM4E | |
| Oxfenicine SCHEMBL3492039 | 0.93 | TDP1 (0.53) | TDP1HSD17B10ALDH1A1KMT2AKDM4E | |
| Oxfenicine SCHEMBL29849367 | 0.88 | SRC (0.58) | TDP1HSD17B10ALDH1A1KMT2AKDM4E | |
| SCHEMBL13527786 | 0.86 | HSD17B10 (0.61) | TDP1HSD17B10ALDH1A1KMT2AKDM4E | |
| SCHEMBL2262988 | 0.77 | HSD17B10 (0.53) | TDP1HSD17B10ALDH1A1KMT2AKDM4E | |
| SCHEMBL5329159 | 0.77 | HSD17B10 (0.53) | TDP1HSD17B10ALDH1A1KMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110869057-A | Ultra-small nanoparticles labeled with zirconium-89 and methods thereof | 纪念斯隆凯特琳癌症中心 | 2020-03-06 | — | — | CN | claimed |
| CN-116648266-A | Oligomeric compounds that specifically bind to proteoglycans | 菲药物股份有限公司 | 2023-08-25 | — | — | CN | disclosed |
| CN-113876962-A | Nanoparticle immunoconjugates | 纪念斯隆-凯特琳癌症中心 | 2022-01-04 | — | — | CN | disclosed |
| CN-107735110-B | Nanoparticle immunoconjugates | 纪念斯隆-凯特琳癌症中心 | 2021-11-26 | — | — | CN | disclosed |
| CN-110869057-A | Ultra-small nanoparticles labeled with zirconium-89 and methods thereof | 纪念斯隆凯特琳癌症中心 | 2020-03-06 | — | — | CN | disclosed |