Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 1/20 | 0.52 |
| ▸ | MAOB | P27338 | 1/20 | 0.52 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | PARP1 | P09874 | 1/20 | 0.34 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.34 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.34 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.34 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.34 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.34 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.34 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.34 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.34 |
| ▸ | GUSB | P08236 | 4/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.33 |
| ▸ | AR | P10275 | 1/20 | 0.33 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2406500 | 0.78 | ALDH1A1 (0.39) | MAOAMAOBATMPARP1HDAC3 | |
| SCHEMBL30255446 | 0.78 | ALDH1A1 (0.39) | MAOAMAOBATMPARP1HDAC3 | |
| SCHEMBL1871722 | 0.78 | PARP1 (0.35) | MAOAMAOBATMPARP1HDAC3 | |
| SCHEMBL1771262 | 0.76 | ANPEP (0.37) | MAOAMAOBATMPARP1HDAC3 | |
| SCHEMBL5625927 | 0.76 | PARP1 (0.34) | MAOAMAOBATMPARP1HDAC3 | |
| SCHEMBL30613493 | 0.76 | PARP1 (0.42) | MAOAMAOBATMPARP1MEN1 | |
| SCHEMBL1771978 | 0.76 | PARP1 (0.34) | MAOAMAOBATMPARP1HDAC3 | |
| SCHEMBL1852029 | 0.76 | PARP1 (0.34) | MAOAMAOBATMPARP1HDAC3 | |
| SCHEMBL6493919 | 0.76 | PARP1 (0.42) | MAOAMAOBATMPARP1MEN1 | |
| SCHEMBL9749865 | 0.76 | HDAC3 (0.46) | ATMHDAC3HDAC4HDAC1HDAC7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110059850-A1 | PHYTOTOXIC HALOGENATED DERIVATIVES OF BENZOXAZINONES | UNIVERSIDAD DE CÁDIZ (ES) | 2011-03-10 | — | — | US | claimed |