SCHEMBL2406500

SCHEMBL2406500

O=C1NOc2ccccc2C1c1ccccc1C1C(=O)NOc2ccccc21

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.39
MEN1 O00255 2/20 0.39
KMT2A Q03164 2/20 0.39
KDM4E B2RXH2 1/20 0.39
TP53 P04637 1/20 0.39
CYP3A4 P08684 1/20 0.39
MAPT P10636 1/20 0.39
PKM P14618 1/20 0.39
HPGD P15428 1/20 0.39
ALOX15 P16050 1/20 0.39
ALOX12 P18054 1/20 0.39
HSD17B10 Q99714 1/20 0.39
CYP2C9 P11712 1/20 0.38
ATM Q13315 1/20 0.37
PARP1 P09874 1/20 0.35
NISCH Q9Y2I1 1/20 0.35
MAOA P21397 1/20 0.34
MAOB P27338 1/20 0.34
IDO1 P14902 1/20 0.33
NPY5R Q15761 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30255446 1.00 ALDH1A1 (0.39) ALDH1A1MEN1KMT2AKDM4ETP53
SCHEMBL5179080 0.89 CYP2C9 (0.34) ALDH1A1MEN1KMT2AKDM4ETP53
SCHEMBL9816846 0.86 LMNA (0.39) ALDH1A1MEN1KMT2AKDM4ETP53
SCHEMBL30262472 0.86 LMNA (0.39) ALDH1A1MEN1KMT2AKDM4ETP53
SCHEMBL1771262 0.82 ANPEP (0.37) ALDH1A1MEN1KMT2AKDM4ETP53
SCHEMBL7688752 0.81 CYP2C9 (0.32) MEN1KMT2ACYP2C9ATM
SCHEMBL1871722 0.79 PARP1 (0.35) ALDH1A1MEN1KMT2AKDM4ETP53
SCHEMBL7746252 0.78 ATM (0.33) ALDH1A1MEN1KMT2AKDM4ETP53
SCHEMBL5625927 0.78 PARP1 (0.34) CYP2C9ATMPARP1MAOAMAOB
SCHEMBL6493919 0.78 PARP1 (0.42) MEN1KMT2AATMPARP1MAOA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 92 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3709966-B1 COMPOSITIONS COMPRISING AT LEAST ONE ACRYLIC POLYMER AND AT LEAST ONE INSOLUBLE ORGANIC SCREENING AGENT OREAL (FR) 2024-12-11 EP claimed
US-20200360264-A1 COMPOSITIONS COMPRISING AT LEAST ONE ACRYLIC POLYMER AND AT LEAST ONE INSOLUBLE ORGANIC SCREENING AGENT L'OREAL (FR) 2020-11-19 US claimed
EP-3709966-A1 COMPOSITIONS COMPRISING AT LEAST ONE ACRYLIC POLYMER AND AT LEAST ONE INSOLUBLE ORGANIC SCREENING AGENT L'Oreal (FR) 2020-09-23 EP claimed
CN-111343968-A Composition comprising at least one acrylic polymer and at least one insoluble organic masking agent 莱雅公司 2020-06-26 CN claimed
CN-105705131-B Cosmetic or dermatological composition comprising a merocyanine and a UV-screening agent 莱雅公司 2019-12-17 CN claimed
EP-2945602-B1 COSMETIC OR DERMATOLOGICAL COMPOSITION COMPRISING A MEROCYANINE AND AN INSOLUBLE ORGANIC UV-SCREENING AGENT AND/OR AN INSOLUBLE INORGANIC UV- SCREENING AGENT L'ORÉAL (FR) 2018-01-10 EP claimed
EP-2945602-A2 COSMETIC OR DERMATOLOGICAL COMPOSITION COMPRISING A MEROCYANINE AND AN INSOLUBLE ORGANIC UV-SCREENING AGENT AND/OR AN INSOLUBLE INORGANIC UV- SCREENING AGENT L'Oréal (FR) 2015-11-25 EP claimed
EP-2872107-A1 COSMETIC COMPOSITION CONTAINING SCREENING COMPOSITE PARTICLES L'Oréal (FR) 2015-05-20 EP claimed
WO-2014111566-A2 COSMETIC OR DERMATOLOGICAL COMPOSITION COMPRISING A MEROCYANINE AND AN INSOLUBLE ORGANIC UV-SCREENING AGENT AND/OR AN INSOLUBLE INORGANIC UV- SCREENING AGENT L'OREAL (FR) 2014-07-24 WO claimed
WO-2014010099-A1 COMPOSITE PIGMENT AND METHOD FOR PREPARING THE SAME L'OREAL (FR) 2014-01-16 WO claimed
US-6818206-B2 CONTROLLING PARTICLE SIZES; TOPICAL APPLYING L'OREAL (FR) 2004-11-16 US claimed
US-20040047820-A1 Synergistically high SPF photoprotective UV-screening compositions comprising insoluble organic sunscreen particles/diarylbutadiene compounds SOCIETE L'OREAL S.A. (FR) 2004-03-11 US claimed
EP-1370232-A2 COSMETIC SOLAR PROTECTION COMPOSITIONS BASED ON A SYNERGIC MIXTURE OF FILTERS AND USES L'OREAL (FR) 2003-12-17 EP claimed
US-6627180-B2 Particles having protection factor UV-APPD and an amino substituted 2-hydroxybenzophenone SOCIETE L'OREAL S.A. (FR) 2003-09-30 US claimed
US-20030152532-A1 SYNERGISTICALLY UV-PHOTOPROTECTING COMPOSITIONS COMPRISING MIXED SCREENING AGENTS SOCIETE L'OREAL S.A. (FR) 2003-08-14 US claimed
US-20030129151-A1 Use of amphiphilic copolymers to stabilize dispersions of insoluble organic compounds for screening out UVradiation, dispersions stabilized with these copolymers and cosmetic compositions containing them L'OREAL (FR) 2003-07-10 US claimed
EP-1317918-A1 Cosmetic sunscreen compositions based on synergistic filter mixture and their use L'OREAL (FR) 2003-06-11 EP claimed
EP-1302197-A1 Use of amphiphilic copolymers to stabilise dispersions of non-soluble organic compounds filtering UV light L'OREAL (FR) 2003-04-16 EP claimed
WO-2002056858-A1 SOLAR PROTECTION COMPOSITIONS L'OREAL (FR) 2002-07-25 WO claimed
WO-2002049597-A2 COSMETIC SOLAR PROTECTION COMPOSITIONS BASED ON A SYNERGIC MIXTURE OF FILTERS AND USES L'OREAL (FR) 2002-06-27 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030129151-A1 Use of amphiphilic copolymers to stabilize dispersions of insoluble organic compounds for screening out UVradiation, dispersions stabilized with these copolymers and cosmetic compositions containing them CUTA, HNRNPU, ERCC5 ALDH1A1 1823/4885MEN1 3351/4885KMT2A 4704/4885
US-20200360264-A1 COMPOSITIONS COMPRISING AT LEAST ONE ACRYLIC POLYMER AND AT LEAST ONE INSOLUBLE ORGANIC SCREENING AGENT PCNA, ERCC1, XRCC6 ALDH1A1 683/4885MEN1 672/4885KMT2A 3095/4885
US-20040047820-A1 Synergistically high SPF photoprotective UV-screening compositions comprising insoluble organic sunscreen particles/diarylbutadiene compounds SUCLG1, CUTA, DLD ALDH1A1 246/4885MEN1 4027/4885KMT2A 3376/4885
US-20030152532-A1 SYNERGISTICALLY UV-PHOTOPROTECTING COMPOSITIONS COMPRISING MIXED SCREENING AGENTS HADHB, SDHA, ERCC4 ALDH1A1 193/4885MEN1 3716/4885KMT2A 3626/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.