SCHEMBL6522180

SCHEMBL6522180

C=C(CC(=O)OCC)C(=O)OCC(=O)OC(C)c1ccccc1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NLRP3 Q96P20 6/20 0.41
CYP2D6 P10635 2/20 0.40
CYP3A4 P08684 1/20 0.40
CYP2C19 P33261 1/20 0.40
MMP8 P22894 1/20 0.40
MAPT P10636 2/20 0.39
ALDH1A1 P00352 2/20 0.39
HCAR2 Q8TDS4 1/20 0.39
MDM4 O15151 1/20 0.38
LMNA P02545 1/20 0.38
MDM2 Q00987 1/20 0.38
MEN1 O00255 1/20 0.38
KMT2A Q03164 1/20 0.38
TDP1 Q9NUW8 1/20 0.37
L3MBTL1 Q9Y468 1/20 0.37
SMN1; SMN2 Q16637 1/20 0.37
SLC6A2 P23975 1/20 0.36
SLC6A4 P31645 1/20 0.36
SLC6A3 Q01959 1/20 0.36
KCNH2 Q12809 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6513820 0.94 HCAR2 (0.41) MAPTALDH1A1HCAR2LMNAKMT2A
SCHEMBL6521140 0.90 KMT2A (0.40) MMP8MAPTALDH1A1HCAR2MEN1
SCHEMBL6518113 0.85 ALDH1A1 (0.48) CYP3A4CYP2C19MAPTALDH1A1LMNA
SCHEMBL6520877 0.84 MMP8 (0.41) NLRP3CYP2D6CYP3A4CYP2C19MMP8
SCHEMBL27843171 0.82 MMP8 (0.49) NLRP3CYP2D6CYP3A4CYP2C19MMP8
SCHEMBL8812407 0.81 HCAR2 (0.46) MAPTALDH1A1HCAR2MEN1KMT2A
SCHEMBL6522589 0.80 TSHR (0.38) LMNAL3MBTL1SMN1; SMN2
SCHEMBL6517409 0.78 ALDH1A1 (0.50) CYP2C19MAPTALDH1A1MEN1KMT2A
SCHEMBL7039893 0.76 ALDH1A1 (0.39) MAPTALDH1A1KMT2AL3MBTL1SMN1; SMN2
SCHEMBL6519486 0.76 ABCB1 (0.45) NLRP3ALDH1A1TDP1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6958366-B2 Antifouling coating composition and novel resin DAINIPPON INK AND CHEMICALS, INC. (JP) 2005-10-25 US disclosed