SCHEMBL6522220

SCHEMBL6522220

C=C(CC(=O)Oc1ccccc1)C(=O)OCC(=O)c1ccccc1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 8/20 0.45
MAPT P10636 5/20 0.45
MEN1 O00255 4/20 0.43
HPGD P15428 3/20 0.43
L3MBTL1 Q9Y468 2/20 0.43
NPC1 O15118 6/20 0.42
RAB9A P51151 5/20 0.42
SMN1; SMN2 Q16637 3/20 0.41
KDM4E B2RXH2 1/20 0.41
CYP3A4 P08684 1/20 0.41
ALOX15 P16050 1/20 0.41
CES1 P23141 1/20 0.41
MAPK1 P28482 1/20 0.41
TDP1 Q9NUW8 1/20 0.41
LMNA P02545 2/20 0.40
ESR1 P03372 1/20 0.40
ESR2 Q92731 1/20 0.40
ALDH1A1 P00352 1/20 0.40
CYP1A2 P05177 1/20 0.40
CYP2C9 P11712 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6519563 0.91 NPC1 (0.53) KMT2AMAPTMEN1L3MBTL1NPC1
SCHEMBL6514457 0.91 NPC1 (0.53) KMT2AMAPTMEN1HPGDL3MBTL1
SCHEMBL6519118 0.89 KMT2A (0.42) KMT2AMAPTMEN1NPC1RAB9A
SCHEMBL6517377 0.88 CYP19A1 (0.41) KMT2AMAPTMEN1HPGDL3MBTL1
SCHEMBL6513324 0.88 KMT2A (0.50) KMT2AMAPTMEN1HPGDL3MBTL1
SCHEMBL6515547 0.85 KMT2A (0.48) KMT2AMAPTMEN1HPGDL3MBTL1
SCHEMBL6515808 0.84 KMT2A (0.44) KMT2AMAPTMEN1L3MBTL1SMN1; SMN2
SCHEMBL6520261 0.84 ELANE (0.40) KMT2AMAPTL3MBTL1ALOX15LMNA
SCHEMBL6522455 0.84 CYP19A1 (0.40) KMT2AMAPTMEN1HPGDALOX15
SCHEMBL6515903 0.83 MAPT (0.48) KMT2AMAPTHPGDL3MBTL1NPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6958366-B2 Antifouling coating composition and novel resin DAINIPPON INK AND CHEMICALS, INC. (JP) 2005-10-25 US disclosed
US-20030118544-A1 Antifouling coating composition and novel resin DAINIPPON INK AND CHEMICALS, INC. (JP) 2003-06-26 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030118544-A1 Antifouling coating composition and novel resin COL1A1, GLRA1, COL2A1 KMT2A 1067/4885MAPT 3438/4885MEN1 3248/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.