Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.30 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18261805 | 0.80 | GABRA1 (0.32) | RAB9AGABRA1GABRB2CYP2C19SMN1; SMN2 | |
| SCHEMBL4423596 | 0.79 | GABRA1 (0.42) | GABRA1GABRB2 | |
| SCHEMBL107782 | 0.78 | CYP1A2 (0.37) | RAB9ACYP2C19SMN1; SMN2NPC1POLB | |
| SCHEMBL7020614 | 0.78 | POLB (0.38) | GABRA1GABRB2CYP2C19SMN1; SMN2NPC1 | |
| SCHEMBL7882053 | 0.77 | CYP2C19 (0.30) | CYP2C19SMN1; SMN2NPC1POLBPTK2B | |
| SCHEMBL8026516 | 0.77 | SMN1; SMN2 (0.41) | MAPTCYP2C19SMN1; SMN2NPC1POLB | |
| SCHEMBL2031068 | 0.77 | CYP1A2 (0.33) | CYP2C19SMN1; SMN2NPC1POLBPTK2B | |
| SCHEMBL3481927 | 0.76 | — | — | |
| SCHEMBL8569204 | 0.75 | NOS3 (0.30) | — | |
| SCHEMBL27649703 | 0.74 | SRC (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1155096-B1 | FLUORENE COPOLYMERS AND DEVICES MADE THEREFROM | DOW GLOBAL TECHNOLOGIES INC (US) | 2005-03-09 | — | — | EP | disclosed |
| US-6353083-B1 | CONJUGATED COPOLYMER COMPRISING UNITS DERIVED FROM 9-SUBSTITUTED FLUORENE MONOMERS AND/OR 9,9-DISUBSTITUTED FLUORENE MONOMERS AND TWO DISTINCT RESIDUAL MONOMERIC UNITS THAT HAVE HOLE TRANSPORTING PROPERTIES | THE DOW CHEMICAL COMPANY | 2002-03-05 | — | — | US | disclosed |
| EP-1155096-A1 | FLUORENE COPOLYMERS AND DEVICES MADE THEREFROM | THE DOW CHEMICAL COMPANY (US) | 2001-11-21 | — | — | EP | disclosed |
| WO-2000046321-A1 | FLUORENE COPOLYMERS AND DEVICES MADE THEREFROM | THE DOW CHEMICAL COMPANY (US) | 2000-08-10 | — | — | WO | disclosed |