SCHEMBL6522563

SCHEMBL6522563

NC(O)(O)c1ccccc1O

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.54
TDP1 Q9NUW8 3/20 0.54
TSHR P16473 3/20 0.54
HPGD P15428 4/20 0.45
HSD17B10 Q99714 4/20 0.45
CA2 P00918 4/20 0.45
ALOX15 P16050 3/20 0.45
KDM4E B2RXH2 3/20 0.45
MAPT P10636 3/20 0.45
LMNA P02545 3/20 0.45
EGFR P00533 2/20 0.45
FYN P06241 2/20 0.45
MMP9 P14780 2/20 0.45
RECQL P46063 2/20 0.45
NPC1 O15118 2/20 0.45
CA4 P22748 2/20 0.45
SMN1; SMN2 Q16637 2/20 0.45
CA12 O43570 1/20 0.45
GMNN O75496 1/20 0.45
POLB P06746 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8089067 0.81 ALDH1A1 (0.56) ALDH1A1TDP1TSHRHPGDHSD17B10
SCHEMBL2059960 0.78 ALDH1A1 (0.59) ALDH1A1TDP1TSHRHPGDHSD17B10
Ethylene SCHEMBL9064414 0.77 ALDH1A1 (0.52) ALDH1A1TDP1TSHRHPGDHSD17B10
SCHEMBL141506 0.77 ALDH1A1 (0.65) ALDH1A1TDP1TSHRHPGDHSD17B10
SCHEMBL30626639 0.77 ALDH1A1 (0.65) ALDH1A1TDP1TSHRHPGDHSD17B10
SCHEMBL9327128 0.76 ALDH1A1 (0.71) ALDH1A1TDP1TSHRHPGDHSD17B10
SCHEMBL8664622 0.75 TSHR (0.50) ALDH1A1TDP1TSHRHPGDHSD17B10
SCHEMBL578112 0.75 ALDH1A1 (0.62) ALDH1A1TDP1TSHRHPGDHSD17B10
SCHEMBL548642 0.74 ALDH1A1 (0.68) ALDH1A1TDP1TSHRHPGDHSD17B10
SCHEMBL526062 0.74 CYP3A4 (0.45) ALDH1A1TDP1TSHRHPGDHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20050009687-A1 Titanium alkoxide catalysts for polymerization of cyclic esters and methods of polymerization NATIONAL SCIENCE FOUNDATION 2005-01-13 US claimed
US-20050009687-A1 Titanium alkoxide catalysts for polymerization of cyclic esters and methods of polymerization NATIONAL SCIENCE FOUNDATION 2005-01-13 US disclosed