Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | CPS1 | P31327 | 1/20 | 0.43 |
| ▸ | HSD11B1 | P28845 | 4/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | NPY2R | P49146 | 1/20 | 0.40 |
| ▸ | PDK2 | Q15119 | 2/20 | 0.39 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.38 |
| ▸ | DPP4 | P27487 | 3/20 | 0.38 |
| ▸ | MGLL | Q99685 | 1/20 | 0.38 |
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.37 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.37 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.37 |
| ▸ | HTR1F | P30939 | 1/20 | 0.36 |
| ▸ | DRD2 | P14416 | 1/20 | 0.36 |
| ▸ | DRD3 | P35462 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6526892 | 0.85 | HSD11B1 (0.52) | HSD11B1ALDH1A1MGLL | |
| SCHEMBL6524778 | 0.81 | GPR6 (0.46) | — | |
| Hydrochloric Acid SCHEMBL2775751 | 0.80 | MEN1 (0.53) | MEN1KMT2ACPS1HSD11B1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL2775749 | 0.80 | MEN1 (0.53) | MEN1KMT2ACPS1HSD11B1ALDH1A1 | |
| SCHEMBL2774895 | 0.77 | KMT2A (0.53) | MEN1KMT2ACPS1HSD11B1ALDH1A1 | |
| SCHEMBL6523336 | 0.77 | GPR6 (0.38) | — | |
| SCHEMBL6524594 | 0.77 | HRH1 (0.46) | — | |
| SCHEMBL6524790 | 0.76 | NAMPT (0.44) | KMT2AMAPT | |
| SCHEMBL6518854 | 0.76 | NAMPT (0.44) | KMT2AMAPT | |
| SCHEMBL6521562 | 0.76 | DPP4 (0.38) | MEN1KMT2ADPP4DPP7DPP8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110053933-A1 | HYDROXYQUINOXALINECARBOXAMIDE DERIVATIVE | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2011-03-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110053933-A1 | HYDROXYQUINOXALINECARBOXAMIDE DERIVATIVE | F12, F2, C3AR1 | MEN1 1623/4885KMT2A 291/4885CPS1 889/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.