Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | CCR1 | P32246 | 8/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | CPS1 | P31327 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | NPY2R | P49146 | 1/20 | 0.42 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | HTR1F | P30939 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2775833 | 0.85 | CCR1 (0.48) | KMT2AMEN1CCR1LMNATSHR | |
| SCHEMBL2777758 | 0.84 | CCR1 (0.59) | KMT2ACCR1LMNATSHRHSD11B1 | |
| Hydrochloric Acid SCHEMBL2775751 | 0.81 | MEN1 (0.53) | KMT2AMEN1CPS1ALDH1A1MAPT | |
| Hydrochloric Acid SCHEMBL2775749 | 0.81 | MEN1 (0.53) | KMT2AMEN1CPS1ALDH1A1MAPT | |
| SCHEMBL2777041 | 0.81 | CCR1 (0.47) | KMT2AMEN1CCR1LMNATSHR | |
| SCHEMBL2774697 | 0.80 | CCR1 (0.49) | CCR1KCNH2 | |
| SCHEMBL22491555 | 0.78 | MEN1 (0.59) | KMT2AMEN1CPS1ALDH1A1MAPT | |
| SCHEMBL2775585 | 0.77 | MEN1 (0.49) | KMT2AMEN1LMNACPS1ALDH1A1 | |
| SCHEMBL1838212 | 0.77 | MEN1 (0.61) | KMT2AMEN1CPS1ALDH1A1MAPT | |
| SCHEMBL6522877 | 0.77 | MEN1 (0.47) | KMT2AMEN1CPS1ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2258697-A1 | HYDROXYQUINOXALINECARBOXAMIDE DERIVATIVE | Daiichi Sankyo Company, Limited (JP) | 2010-12-08 | — | — | EP | disclosed |