SCHEMBL6522899

SCHEMBL6522899

O=C(O)Cn1c(=O)[nH]c(=O)n(CC(=O)O)c1=O

nearest known ligand 0.63

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
APEX1 P27695 2/20 0.63
GRIN1 Q05586 3/20 0.39
GRIN2B Q13224 3/20 0.39
GRIN2D O15399 2/20 0.39
GRIN3B O60391 2/20 0.39
GRIA1 P42261 2/20 0.39
GRIA2 P42262 2/20 0.39
GRIA3 P42263 2/20 0.39
GRIA4 P48058 2/20 0.39
GRIN2A Q12879 2/20 0.39
GRIN2C Q14957 2/20 0.39
GRIN3A Q8TCU5 2/20 0.39
GLA P06280 1/20 0.38
KDM4E B2RXH2 3/20 0.38
TSHR P16473 1/20 0.38
KMT2A Q03164 2/20 0.35
ALDH1A1 P00352 2/20 0.35
HPGD P15428 2/20 0.35
MEN1 O00255 1/20 0.34
ACE P12821 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29251527 0.90 APEX1 (0.53) APEX1GRIN1GRIN2BGRIN2DGRIN3B
SCHEMBL29251528 0.86 APEX1 (0.53) APEX1GRIN1GRIN2BGRIN2DGRIN3B
SCHEMBL29251937 0.84 APEX1 (0.56) APEX1KDM4EALDH1A1HPGDADORA2B
SCHEMBL677187 0.82 APEX1 (0.62) APEX1GLAKDM4ETSHRKMT2A
SCHEMBL4184455 0.81 APEX1 (0.47) APEX1GRIN1GRIN2BGRIN2DGRIN3B
SCHEMBL21176778 0.79 APEX1 (0.50) APEX1POLBSMN1; SMN2
SCHEMBL29251945 0.78 NTRK1 (0.50) APEX1GLAKDM4ETSHRKMT2A
SCHEMBL677227 0.77 APEX1 (1.00) APEX1KDM4EKMT2AALDH1A1HPGD
SCHEMBL7337432 0.75 APEX1 (0.45) APEX1GRIN1GRIN2BGRIN2DGRIN3B
SCHEMBL6520401 0.74 APEX1 (0.78) APEX1KDM4EALDH1A1HPGDPOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6841305-B2 High temperature, storage stability MATSUSHITA ELECTRIC INDUSTRIAL CO., LTD. (JP) 2005-01-11 US disclosed
US-20020009652-A1 High temperature, storage stability MATSUSHITA ELECTRIC INDUSTRIAL CO., LTD. (JP) 2002-01-24 US disclosed
EP-1160899-A2 Non-aqueous electrolyte battery and non-aqueous electrolyte MATSUSHITA ELECTRIC INDUSTRIAL CO., LTD. (JP) 2001-12-05 EP disclosed