Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | C5AR1 | P21730 | 20/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6523352 | 0.79 | C5AR1 (0.38) | C5AR1 | |
| SCHEMBL6525743 | 0.77 | LTB4R (0.33) | C5AR1 | |
| SCHEMBL3816531 | 0.72 | GAA (0.40) | — | |
| SCHEMBL1328686 | 0.72 | C5AR1 (0.47) | C5AR1 | |
| SCHEMBL6522128 | 0.72 | C5AR1 (0.31) | C5AR1 | |
| SCHEMBL1326973 | 0.70 | C5AR1 (0.43) | C5AR1 | |
| SCHEMBL1328338 | 0.69 | C5AR1 (0.41) | C5AR1 | |
| SCHEMBL1330008 | 0.68 | C5AR1 (0.44) | C5AR1 | |
| SCHEMBL1327957 | 0.68 | C5AR1 (0.38) | C5AR1 | |
| SCHEMBL1327289 | 0.68 | C5AR1 (0.41) | C5AR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1565452-A2 | 3-SUBSTITUTED-6-ARYL PYRIDINES AS LIGANDS OF C5A RECEPTORS | NEUROGEN CORPORATION (US) | 2005-08-24 | — | — | EP | disclosed |
| WO-2004043925-A2 | 3-SUBSTITUTED-6-ARYL PYRIDINED AS LIGANDS OF C5A RECEPTORS | NEUROGEN CORPORATION (US) | 2004-05-27 | — | — | WO | disclosed |