SCHEMBL6523404

SCHEMBL6523404

O=C1Nc2ccccc2C1=C1C(=O)Oc2cc3c(cc21)OC(=O)C3=C1C(=O)Nc2ccccc21

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LRRK2 Q5S007 4/20 0.48
ACVR1 Q04771 2/20 0.48
MAOA P21397 1/20 0.48
MAOB P27338 1/20 0.48
PDGFRA P16234 1/20 0.48
FER P16591 1/20 0.48
LTK P29376 1/20 0.48
CDK8 P49336 1/20 0.48
DYRK1B Q9Y463 1/20 0.48
NTRK1 P04629 1/20 0.43
CCNA2 P20248 1/20 0.43
CDK2 P24941 1/20 0.43
CCNA1 P78396 1/20 0.43
CSNK1G1 Q9HCP0 1/20 0.41
CHEK1 O14757 1/20 0.41
MAPT P10636 5/20 0.41
ALDH1A1 P00352 4/20 0.41
L3MBTL1 Q9Y468 3/20 0.41
POLB P06746 2/20 0.41
TDP1 Q9NUW8 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10295101 1.00 LRRK2 (0.48) LRRK2ACVR1MAOAMAOBPDGFRA
SCHEMBL10295294 1.00 LRRK2 (0.48) LRRK2ACVR1MAOAMAOBPDGFRA
SCHEMBL29383535 1.00 LRRK2 (0.48) LRRK2ACVR1MAOAMAOBPDGFRA
SCHEMBL10295095 1.00 LRRK2 (0.48) LRRK2ACVR1MAOAMAOBPDGFRA
Cyanide SCHEMBL21357786 0.95 LRRK2 (0.44) LRRK2ACVR1MAOAMAOBPDGFRA
Cyanide SCHEMBL21357787 0.95 LRRK2 (0.44) LRRK2ACVR1MAOAMAOBPDGFRA
SCHEMBL7092480 0.90 LRRK2 (0.48) LRRK2ACVR1MAOAMAOBPDGFRA
SCHEMBL7092479 0.90 LRRK2 (0.48) LRRK2ACVR1MAOAMAOBPDGFRA
SCHEMBL18532164 0.86 NTRK1 (0.41) LRRK2ACVR1MAOAMAOBPDGFRA
SCHEMBL25587191 0.86 CDK2 (0.43) LRRK2ACVR1MAOAMAOBPDGFRA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3765457-A1 3,7-BIS(2-OXOINDOLIN-3-YLIDENE)BENZO[1,2-B:4,5-B']DIFURAN-2,6-DIONE DICYANIDE-BASED MATERIALS AND USES THEREOF IN ORGANIC ELECTRONIC DEVICES National Research Council of Canada (CA) 2021-01-20 EP disclosed
EP-3765457-A1 3,7-BIS(2-OXOINDOLIN-3-YLIDENE)BENZO[1,2-B:4,5-B']DIFURAN-2,6-DIONE DICYANIDE-BASED MATERIALS AND USES THEREOF IN ORGANIC ELECTRONIC DEVICES National Research Council of Canada (CA) 2021-01-20 EP disclosed
US-20210013424-A1 3,7-BIS(2-OXOINDOLIN-3-YLIDENE)BENZO[1,2-B:4,5-B']DIFURAN-2,6-DIONE DICYANIDE-BASED MATERIALS AND USES THEREOF IN ORGANIC ELECTRONIC DEVICES NATIONAL RESEARCH COUNCIL OF CANADA (CA) 2021-01-14 US disclosed
WO-2019175804-A1 3,7-BIS(2-OXOINDOLIN-3-YLIDENE)BENZO[1,2-B:4,5-B']DIFURAN-2,6-DIONE DICYANIDE-BASED MATERIALS AND USES THEREOF IN ORGANIC ELECTRONIC DEVICES NATIONAL RESEARCH COUNCIL OF CANADA (CA) 2019-09-19 WO disclosed
WO-2019175804-A1 3,7-BIS(2-OXOINDOLIN-3-YLIDENE)BENZO[1,2-B:4,5-B']DIFURAN-2,6-DIONE DICYANIDE-BASED MATERIALS AND USES THEREOF IN ORGANIC ELECTRONIC DEVICES NATIONAL RESEARCH COUNCIL OF CANADA (CA) 2019-09-19 WO disclosed
US-20160099412-A1 N-TYPE ORGANIC SEMICONDUCTOR FORMULATIONS AND DEVICES LI YUNING (CA) 2016-04-07 US disclosed
US-6858073-B2 Pigmented vitreous material CIBA SPECIALTY CHEMICALS CORPORATION (US) 2005-02-22 US disclosed
US-20040159265-A1 Pigmented vitreous material BUJARD PATRICE (CH) 2004-08-19 US disclosed
US-6737533-B2 DISPERSION OF PIGMENT IN VITREOUS COMPOUND; CONTROLLED HEATING CIBA SPECIALTY CHEMICALS CORPORATION 2004-05-18 US disclosed
EP-1400496-A1 Pigment precursors for making pigmented vitreous material Ciba SC Holding AG (CH) 2004-03-24 EP disclosed
US-6524382-B1 Crosslinking organic pigment or chromophore with transition metal compound CIBA SPECIALTY CHEMICALS CORPORATION 2003-02-25 US disclosed
EP-1242327-A1 PIGMENTED VITREOUS MATERIAL ITS PRECURSOR GLASS ITEMS COATED THEREWITH AND METHOD OF ITS PREPARATION Ciba SC Holding AG (CH) 2002-09-25 EP disclosed
WO-2001032577-A1 PIGMENTED VITREOUS MATERIAL ITS PRECURSOR GLASS ITEMS COATED THEREWITH AND METHOD OF ITS PREPARATION CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 2001-05-10 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210013424-A1 3,7-BIS(2-OXOINDOLIN-3-YLIDENE)BENZO[1,2-B:4,5-B']DIFURAN-2,6-DIONE DICYANIDE-BASED MATERIALS AND USES THEREOF IN ORGANIC ELECTRONIC DEVICES TDO2, SCO2, DBF4 LRRK2 2570/4885ACVR1 4444/4885MAOA 2530/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.