SCHEMBL6523486

SCHEMBL6523486

C=C(C)C(=O)O[SiH](C)O[Si](C)(C)C

nearest known ligand 0.39

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.39
TSHR P16473 1/20 0.32
THRB P10828 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6253378 0.81 ALDH1A1 (0.41) ALDH1A1TSHRTHRB
Methacrylic Acid SCHEMBL28366164 0.78 ALDH1A1 (0.32) ALDH1A1
SCHEMBL550562 0.78 TSHR (0.31) ALDH1A1TSHR
SCHEMBL2779555 0.76 ALDH1A1 (0.44) ALDH1A1TSHRTHRB
SCHEMBL3898586 0.76 ALDH1A1 (0.50) ALDH1A1TSHRTHRB
SCHEMBL1273423 0.75 ALDH1A1 (0.35) ALDH1A1TSHRTHRB
SCHEMBL11133119 0.73 ALDH1A1 (0.60) ALDH1A1TSHR
SCHEMBL10432431 0.72 ALDH1A1 (0.41) ALDH1A1TSHRTHRB
SCHEMBL6137384 0.72
SCHEMBL10897664 0.70

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101213070-B Rapid replication process and radiation curable composition for use therein UNIV WIEN TECH 2012-06-27 CN claimed
CN-101065157-B Biomedical devices containing amphiphilic block copolymers JOHNSON & JOHNSON VISION CARE 2012-01-04 CN claimed
CN-101213070-A Rapid replication process and radiation curable composition for use therein UNIV WIEN TECH (AT) 2008-07-02 CN claimed
CN-101065157-A Biomedical devices containing amphiphilic block copolymers JOHNSON & JOHNSON VISION CARE (US) 2007-10-31 CN claimed
CN-1842559-A Silicone hydrogels containing stable concentrations of multifunctional polysiloxanes JOHNSON & JOHNSON VISION CARE (US) 2006-10-04 CN claimed
CN-1170871-C Siloxanes aquogel polymer 庄臣及庄臣视力产品有限公司 2004-10-13 CN claimed
CN-1231303-A Siloxanes aquogel polymer JOHNSON & JOHNSON VISION PROD (US) 1999-10-13 CN claimed
CN-102576158-B Silicone hydrogel contact lenses and methods of making silicone hydrogel contact lenses COOPERVISION INT HOLDING CO LP 2014-07-16 CN disclosed
CN-102690419-B Silicon-containing prepolymer and silicone hydrogel biomaterial containing same ZHAN QIANQING 2014-05-07 CN disclosed
CN-103543539-A Method for reducing cornea pollution of contact lens wearer JOHNSON & JOHNSON VISION CARE 2014-01-29 CN disclosed
CN-101151569-B Method for reducing corneal contamination of contact lens wearer ZHUANGCHEN AND ZHUANGCHEN EYESIGHT PROT COMPANY 2013-11-20 CN disclosed
CN-101910254-B Polyorganosiloxane containing methacryloxy group or acryloxy group and method for producing the same DOW CORNING TORAY CO LTD 2013-01-09 CN disclosed
CN-102690419-A Silicon-containing prepolymer and silicone hydrogel biomaterial containing same QIANQING ZHAN 2012-09-26 CN disclosed
CN-1906222-A Novel prepolymers for improved surface modification of contact lenses BAUSCH & LOMB (US) 2007-01-31 CN disclosed
CN-1260255-C Method for polymerizing lenses BAUSCH & LOMB (US) 2006-06-21 CN disclosed
CN-1735502-A Methods for the extraction of contact lenses JOHNSON & JOHNSON VISION CARE (US) 2006-02-15 CN disclosed
EP-1604231-A1 PHOTOCHROMIC OCULAR DEVICES TRANSITIONS OPTICAL, INC. (US) 2005-12-14 EP disclosed
CN-1582303-A Method of polymerizing lenses BAUSCH & LOMB (US) 2005-02-16 CN disclosed
WO-2004086103-A1 PHOTOCHROMIC OCULAR DEVICES TRANSITIONS OPTICAL INC. (US) 2004-10-07 WO disclosed
CN-1301353-A Method of polymerizing contact lenses BAUSCH & LOMB INCORP (US) 2001-06-27 CN disclosed